放射性口腔黏膜炎的发生机制及防治研究进展  

Progress in the pathogenesis and prevention of radiation induced oral mucositis

作　　者：李曼[1] 赵钦[1] 魏金龙[1] 姜新[1] Li Man;Zhao Qin;Wei Jinlong;Jiang Xin(Department of Radiation Oncology,the First Hospital of Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学第一医院放疗科,长春130021

出　　处：《中华放射肿瘤学杂志》2024年第1期79-84,共6页Chinese Journal of Radiation Oncology

基　　金：吉林省科技厅项目(20230508064RC);吉林省医疗卫生人才专项(JLSWSRCZX 2023-68)。

摘　　要：放疗是头颈部肿瘤患者主要的治疗方式之一,放射性口腔黏膜炎(RIOM)是头颈部肿瘤患者在放疗过程中出现的常见并发症之一,它是一种与吞咽困难和口腔疼痛相关的黏膜损伤反应,严重时会影响患者的生存质量和预后。因此预防和治疗RIOM至关重要,本文从RIOM的发病机制、临床表现、治疗与预防方法进行归纳总结,旨在为头颈部肿瘤患者由于放疗所引起的口腔黏膜炎的治疗提供指导。Radiotherapy is the main treatment for patients with head and neck cancer.Radiation-induced oral mucositis(RIOM)is one of the common complications of patients with head and neck cancer during radiotherapy.It is a mucus injury reaction related to dysphagia and oral pain,which will affect the quality of life and prognosis of patients when it becomes severe.Therefore,prevention and treatment of RIOM are of significance for patients.In this article,the pathogenesis,clinical manifestations,treatment and prevention methods of RIOM were summarized,aiming to provide guidance for the treatment of oral mucositis caused by radiotherapy in patients with head and neck cancer.

关 键 词：头颈部肿瘤 放射疗法 放射性口腔黏膜炎 

分 类 号：R730.55[医药卫生—肿瘤]