银杏叶提取物对淡水石斑鱼血清生化指标和肝功能的影响  

Effect of Ginkgo biloba extract on serum biochemical index and liver function of Cichlasoma managuense

作　　者：陆宇杰 熊锐 孙玉梅 冯洪超 孙学亮 尤宏争[3] 毕相东 郭永军 LU Yu-jie;XIONG Rui;SUN Yu-mei;FENG Hong-chao;SUN Xue-liang;YOU Hong-zheng;BI Xiang-dong;GUO Yong-jun

机构地区：[1]天津农学院水产学院天津市水产生态及养殖重点实验室,天津300392 [2]天津市宝坻区农业发展服务中心,天津301899 [3]天津市水产研究所,天津301636

出　　处：《饲料研究》2024年第1期44-48,共5页Feed Research

基　　金：天津市科技计划项目(项目编号:22ZYCGSN00240);甘肃省科技计划项目(项目编号:22CX8NE208);天津市科技援助项目(项目编号:22ZYCGSN00050)。

摘　　要：试验旨在探究不同水平银杏叶提取物(EGB)对淡水石斑鱼血清抗氧化功能、肝功能、血脂代谢及血清葡萄糖的影响。选取平均体重为(60.30±0.25)g的淡水石斑鱼240尾,随机分为4组,每组3个重复,每个重复20尾,G0组(对照组)、G1组、G2组和G3组分别在基础饲料中添加0、50、100、200 mg/kg的EGB。试验期28 d。结果显示,试验21 d时,与对照组相比,G2组试验鱼血清中总超氧化物歧化酶(T-SOD)、谷胱甘肽过氧化物酶(GSH-Px)活性及血清高密度脂蛋白胆固醇(HDL-C)含量提高(P<0.05);试验14~21 d时,与对照组相比,G2组试验鱼血清葡萄糖(GLU)、低密度脂蛋白胆固醇(LDL-C)、总胆固醇(CHO)、甘油三酯(TG)和丙二醛(MDA)的含量及过氧化氢酶(CAT)、谷丙转氨酶(ALT)和谷草转氨酶(AST)活性降低(P<0.05)。研究表明,饲料中添加EGB可以调节淡水石斑鱼血脂代谢,增强淡水石斑鱼的抗氧化能力,可用于预防和治疗高脂血症,EGB添加量为100 mg/kg时投喂14~21 d效果较好。The study was to investigate the effect of various levels of Ginkgo biloba extract(EGB)on the serum antioxidant function,liver function,lipid metabolism,and serum glucose of Cichlasoma managuense.A total of 240 Cichlasoma managuense with an average weight of(60.30±0.25)g were selected and randomly divided into four groups,with three replicates in each group and 20 fish in each replicate.The G0 group(control group),G1 group,G2 group,and G3 group were supplemented with 0,50,100,and 200 mg/kg EGB of in the basic feed.The experimental period lasted for 28 days.The results showed that the activity of T-SOD,GSH-Px and the content of HDL-C in the serum of test fish in the G2 group were higher than those of the control group at 21 days(P<0.05).Compared with the control group,the content of GLU,LDL-C,CHO,TG and MDA and the activity of CAT,ALT and AST in the G2 group were reduced(P<0.05).The study indicates that the addition of EGB to the feed can regulate blood lipid metabolism and improve the antioxidant capacity of Cichlasoma managuense,which can be used to prevent and treat hyperlipidemia.The optimal EGB dosage is 100 mg/kg for 14~21 days.

关 键 词：淡水石斑鱼 银杏叶提取物 免疫功能 抗氧化功能 血清葡萄糖 

分 类 号：S963[农业科学—水产养殖]