Supramolecular cyclization induced emission enhancement in a pillar[5]arene probe for discrimination of spermine  

作　　者：Yibin Zhou Hao Tang Hanlun Wu Xiaomei Jiang Lingyun Wang Derong Cao 

机构地区：[1]State Key Laboratory of Luminescent Materials and Devices,School of Chemistry and Chemical Engineering,South China University of Technology,Guangzhou 510641,China

出　　处：《Chinese Chemical Letters》2024年第1期275-279,共5页中国化学快报（英文版）

基　　金：the National Natural Science Foundation of China(Nos.22071066,22071065);the National Key Research and Development Program of China(No.2016YFA0602900);the Guangdong Natural Science Foundation,China(No.2018B030311008);the Guangzhou Science and Technology Project,China(No.202102020802).

摘　　要：Early diagnosis and treatment of cancer requires the development of tools that are both sensitive and selective in detecting spermine.In this study,we presented a"supramolecular cyclization-induced emission enhancement"strategy for the sensitive and selective detection of spermine.A new pillar[5]arene probe(P1)demonstrated excellent solution/solid dual-state emission properties,and the addition of certain spermine(Spm)resulted in fluorescence enhancement due to the synergy of multiple weak interactions that restricted the free motion of P1 in the P1⊃Spm complex.This mechanism was further confirmed by time-resolved spectroscopy,DFT calculations,and IGM analysis.With its low limit of detection and high selectivity,P1 is a promising tool for measuring spermine in artificial urine samples.

关 键 词：SPERMINE arene PROBE Supramolecular chemistry Supramolecular cyclization induced emission enhancement 

分 类 号：TQ241[化学工程—有机化工]