support of the National Natural Science Foundation of China(No.22361011)。
A supramolecular assembly composed of perylene diimide derivative(PDI-nm)and nor-secocucurbit[10]uril(ns-Q[10])was designed.The excellent host-guest interaction between PDI-nm and nsQ[10]prevented the aggregation-caus...
supported by the National Natural Science Foundation of China(No.51872030).
Spermine assumes a pivotal role in assessing food safety due to its potential to induce a spectrum of diseases upon excessive consumption.However,contemporary spermine detection methodologies,exemplified by high-perfo...
the Natural Science Foundation of Zhejiang Province(Nos.LR24B020003 and LQ24B020003);the National Natural Science Foundation of China(No.21921003)for financial support。
Reported here is the synthesis of a new macrocycle bearing anionic carboxylate groups with water-soluble aggregation-induced emission(AIE).The water-soluble macrocycle without typical AIE luminogens is constructed bas...
supported by the Science and Technology Innovation Team Talent Project of Hunan Province(No.2021RC4056);the clinical research foundation of the National Clinical Research Center for Geriatric Diseases(XIANGYA)(No.2020LNJJ01);the Natural Science Foundation of Hunan Province in China(No.2021JJ20084);the Science and Technology Innovation Program of Hunan Province(No.2021RC3020)。
Polyamine metabolism dysregulation is a hallmark of many cancers,offering a promising avenue for early tumor theranostics.This study presents the development of a nuclear probe derived from spermidine(SPM)for dual-pur...
Fluorescent poly(N-isopropylacrylamide-co-Nile blue)(pNIPAm-co-NB)microgels were synthesized that exhibited fluorescence intensity changes in a water temperature-dependent fashion.NB is well known to exhibit fluoresce...
supported by the National Natural Science Foundation of China (81921002,81900970,82130027);Innovative Research Team of High-Level Local Universities in Shanghai (SHSMUZLCX20212400);Young Physician Innovation Team Project (QC202003)of Ninth People’s Hospital affiliated to Shanghai Jiao Tong University School of Medicine;Shanghai“Rising Stars of Medical Talent”Youth Development Program is also acknowledged。
Osteoporosis(OP)is a prevalent metabolic bone disease.While drug therapy is essential to prevent bone loss in osteoporotic patients,current treatments are limited by side effects and high costs,necessitating the devel...
the National Natural Science Foundation of China(Nos.22071066,22071065);the National Key Research and Development Program of China(No.2016YFA0602900);the Guangdong Natural Science Foundation,China(No.2018B030311008);the Guangzhou Science and Technology Project,China(No.202102020802).
Early diagnosis and treatment of cancer requires the development of tools that are both sensitive and selective in detecting spermine.In this study,we presented a"supramolecular cyclization-induced emission enhancemen...
supported by National Science Foundation Grants(OCE1029607 to X.M)and Kent State University.
Short-chained aliphatic polyamines (PAs) have recently been recognized as an important carbon, nitrogen, and/or energy source for marine bacterioplankton. To study the genes and taxa involved in the transformations of...
This research is supported by the Sichuan Science and Technology Program(No.2020YJ0398).
Weaning stress can cause tight junctions damage and intestinal permeability enhancement,which leads to intestinal imbalance and growth retardation,thereby causing damage to piglet growth and development.Spermine can r...
Polyamines play preeminent roles in a variety of cellular functions in the central nervous system and other organs.A large body of evidence suggests that the polyamine pathway is prominently involved in the etiology a...