FS-T_(2)WI联合DWI在乳腺良恶性囊实性病变鉴别诊断中的价值  

Value of FS-T_(2WI) combined with DWI in the differential diagnosis of benign and malignant cystic solid lesions of the breast

作　　者：郑海龙[1] 严高武 ZHENG Hai-long;YAN Gao-wu(Department of Radiography,Suining Central Hospital,Suining Sichuan 629000,China)

机构地区：[1]遂宁市中心医院放射影像科,四川遂宁629000

出　　处：《中国临床医学影像杂志》2024年第1期31-34,共4页Journal of China Clinic Medical Imaging

基　　金：四川省卫生健康委员会科研课题(编号:19PJ284)。

摘　　要：目的:探究T_(2)WI抑脂序列(Fat saturation T_(2)-weighted imaging,FS-T_(2)WI)联合扩散加权成像(Diffusion weighted imaging,DWI)在乳腺良恶性囊实性病变鉴别诊断中的价值。方法:回顾性选取2021年1月—2022年12月于我院治疗的乳腺囊实性病变患者95例,病灶数量113个。于治疗前对患者行FS-T_(2)WI和DWI序列扫描,对影像学图像进行分析,获取ADC值和FS-T_(2)WI不均匀,以手术病理检查结果为金标准,采用受试者工作曲线(ROC)分析FS-T_(2)WI和DWI序列扫描对乳腺良恶性囊实性病变的鉴别效能。结果:对95例患者行病理组织活检,有38例患者存在恶性结节,57例患者无恶性结节,根据此结果将患者分为良性组和恶性组,比较两组患者资料发现,恶性组患者的结节数量明显多于良性组,最大肿瘤直径大于良性组(P<0.05)。病理检查结果显示共有113个结节,其中恶性结节48个,良性结节65个。根据结节性质不同将结节分为良性结节和恶性结节,比较不同结节的FS-T_(2)WI和DWI序列扫描结果发现,良恶性结节囊壁特点、厚度和肿瘤内部强化特征之间差异有统计学意义,且恶性结节平均直径大于良性结节,ADC值和SIR值小于良性结节(P<0.05)。ADC值和SIR值对乳腺囊实性良恶性病变的诊断AUC分别为0.801、0.818,两者联合检测的AUC为0.908,其联合诊断灵敏度和特异度分别为81.3%、86.3%,高于单独诊断的诊断效能。结论:FS-T_(2)WI和DWI序列扫描对于乳腺囊实性良恶性病变均有较高的鉴别诊断价值,且两者联合诊断的灵敏度和特异度均高于单独诊断。Objective:To explore the value of fat saturation T_2-weighted imaging(FS-T_2WI) combined with diffusion weighted imaging(DWI) in the differential diagnosis of benign and malignant cystic and solid lesions of the breast.Methods:A retrospective study was conducted on 95 cases with cystic and solid lesions of breast treated in our hospital from January 2021to December 2022,with a total of 113 lesions.Before treatment,the patients were scanned with FS-T_(2WI) and DWI sequence,and the images were analyzed to obtain ADC values and FS-T_(2WI) nonuniformity.The results of surgical pathology were used as the gold standard.The receiver operator curve(ROC) was used to analyze the differential efficacy of FS-T_(2WI) and DWI sequence scanning in benign and malignant cystic and solid breast disease.Results:Pathological tissue biopsies were performed on 95 cases,38 cases had malignant nodules and 57 cases had no malignant nodules.According to the results,the patients were divided into benign group and malignant group.Comparing the data of patients in the two groups,it was found that the number of nodules in the malignant group was significantly greater than that in the benign group,and the diameter of the largest tumor was larger than that in the benign group(P<0.05).Pathological examination showed that there were 113 nodules,including 48 malignant nodules and 65 benign nodules.According to the different nature of the nodules,they were divided into benign and malignant nodules.Comparing the FS-T_(2WI) and DWI sequence scanning results of different nodules,it was found that there were statistically significant differences in the characteristics,thickness,and internal enhancement characteristics of the cyst wall between benign and malignant nodules.The average diameter of malignant nodules was larger than that of benign nodules,and the ADC and SIR values were smaller than those of benign nodules(P<0.05).The AUC of ADC value and SIR value for the diagnosis of benign and malignant cystic and solid breast lesions were 0.801 and 0.81

关 键 词：乳腺肿瘤 乳腺疾病 磁共振成像 

分 类 号：R737.9[医药卫生—肿瘤] R445.2[医药卫生—临床医学]