沙门氏菌血清分型及耐药机制研究进展  

Research Progress on Serotyping and AntimicrobialResistance Mechanism of Salmonella

作　　者：王贤文 赵丽媛 张瑞雪 邹明[1] 邵长军 刘刚 Wang Xianwen;Zhao Liyuan;Zhang Ruixue;Zou Ming;Shao Changjun;Liu Gang(College of Veterinary Medicine,Qingdao Agricultural University,Qingdao 266109,China;Yantai Academy of Agricultural Sciences,Yantai 264000,China)

机构地区：[1]青岛农业大学动物医学院,山东青岛266109 [2]烟台市农业科学研究院,山东烟台264000

出　　处：《山东农业科学》2024年第1期174-180,共7页Shandong Agricultural Sciences

基　　金：国家自然科学基金青年基金项目(32200151);山东省自然科学基金青年基金项目(ZR2022QC043);山东省重点研发计划子课题(2022CXGC010606-01-05);青岛农业大学高层次人才科研启动基金项目(665-1122009)。

摘　　要：沙门氏菌(Salmonella)是常见的能引起食源性疾病的人畜共患病原菌,其抗生素耐药性已成为全球公共卫生安全面临的主要挑战之一,严重危害公共健康和食品安全。文章重点阐述了近年来常见的沙门氏菌血清型及血清型分型技术研究进展,并对兽医临床主要抗菌剂的耐药机制进行综述,为进一步了解我国沙门氏菌优势血清型及其对各类药物的耐药机制、降低细菌耐药性的发生和传播、预防食源性污染提供理论支撑,也为沙门氏菌感染溯源及防控提供参考。Salmonella is a common zoonotic pathogen which can cause foodborne diseases.Antimicrobial resistance of Salmonella has become one of the major challenges to global public health safety,and would en-danger public health and food safety seriously.In this paper,the research progress of common serotypes and serotyping technology of Salmonella in recent years,and the antimicrobial resistance mechanisms in veterinary clinics were reviewed.These would provide theoretical foundations for further understanding the dominant Sal-monella serotypes and their resistance mechanisms to common antibiotics,reducing the occurrence and spread of antimicrobial resistance,and preventing foodborne contamination in China,as well as providing references for tracing and prevention of Salmonella infection.

关 键 词：沙门氏菌 血清型 分型方法 耐药机制 

分 类 号：S852.61[农业科学—基础兽医学]