Epidemiology and early screening strategies for colorectal cancer in China  

作　　者：Yong Yang Zhaoya Gao An Huang Jingyi Shi Zhuang Sun Haopeng Hong Jin Gu 

机构地区：[1]Department of Gastrointestinal Surgery,Peking University Shougang Hospital,Beijing 100144,China [2]Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education/Beijing),Gastrointestinal Cancer Center,Peking University Cancer Hospital&Institute,Beijing 100142,China

出　　处：《Chinese Journal of Cancer Research》2023年第6期606-617,共12页中国癌症研究（英文版）

摘　　要：China ranks the first worldwide in the number of new colorectal cancer(CRC) cases and CRC-related deaths. The increasing incidence of early-onset CRC in recent years highlights the challenges related to CRC screening and prevention. High-quality colonoscopy is the universally used gold standard for CRC screening. Risk assessment combined with a two-step screening strategy based on colonoscopy and non-invasive examinations was proven to be highly effective. However, systematic use of well-established risk factors associated with CRC, beyond age, could better identify those who might harbor advanced colorectal neoplasia, improve the diagnostic yield of current screening modalities, and optimize the selection of individuals who might benefit most from preventive strategies.“Personalization” and “Standardization” are the future development directions of CRC screening, from the initiation of screening in those at high risk for CRC to follow-up after treatment, which are the key to ensure the screening efficiency.

关 键 词：Colorectal cancer EPIDEMIOLOGY early screening REVIEW 

分 类 号：R735.34[医药卫生—肿瘤] R181.3[医药卫生—临床医学]