目标导向液体干预对老年胃肠道肿瘤患者术后血流动力学、胃肠功能恢复的影响  

Effect of target-directed liquid intervention on postoperative hemodynamics and gastrointestinal function recovery in elderly patients with gastrointestinal tumors

作　　者：李凤仪 李若凡[1] 高旭[1] 张超凡 Li Fengyi;Li Ruofan;Gao Xu;Zhang Chaofan(Department of the Second General Surgery,Beijing Luhe Hospital,Capital Medical University,Beijing 101149,China)

机构地区：[1]首都医科大学附属北京潞河医院普外二科,北京101149

出　　处：《中华普外科手术学杂志（电子版）》2024年第1期29-32,共4页Chinese Journal of Operative Procedures of General Surgery(Electronic Edition)

基　　金：首都医科大学附属北京路河医院临床研究项目(2020-KY-042)。

摘　　要：目的探究目标导向液体干预对老年胃肠道肿瘤患者术后血流动力学、胃肠功能恢复的影响。方法回顾性分析2019年5月至2022年5月97例老年胃肠道肿瘤患者临床资料,根据干预方式不同将患者分为两组,对照组(n=49)采用常规液体干预,试验组(n=48)采用目标导向液体干预。采用SPSS 28.0软件进行数据统计与分析,围手术期情况、术后血流动力学、胃肠功能恢复相关指标以()表示,采用独立样本t检验;并发症发生情况等计数资料以[例(%)]表示,采用χ2 检验。P<0.05表示差异有统计学意义。结果试验组患者胶体液及晶体液用量、尿量、住院时间均少于对照组(P<0.05);试验组患者平均动脉压(MAP)高于对照组,心率(HR)低于对照组(P<0.05);试验组患者首次排气、肠鸣音恢复及进食时间均短于对照组(P<0.05);两组患者术后并发症包括心功能不全、肺部感染、心律失常、少尿或无尿,试验组患者并发症发生率(10.4%)显著低于对照组的(28.6%)(P<0.05)。结论目标导向液体干预利于老年胃肠道肿瘤患者术后康复与胃肠功能恢复、可改善血流动力学并降低并发症发生风险,可用于临床推广。ObjectiveThis study was conducted to investigate the effect of target-directed liquid intervention on postoperative hemodynamics and gastrointestinal function recovery in elderly patients with gastrointestinal tumors.MethodsA retrospective study from May 2019 to May 2022 was conducted and 97 elderly patients with gastrointestinal tumors were included in the study. Patients receiving routine liquid intervention and those receiving target-directed liquid intervention were included in the control group (n=49) and the experimental group (n=48), respectively. Statistical data analysis was performed using SPSS 28.0 software. Perioperative condition, postoperative hemodynamics and gastrointestinal function recovery related indicators were compared by independent-samples t test. The incidence of complications was analyzed by χ2 test. P<0.05 indicated that the difference was statistically significant.ResultsThe dosages of colloid solution and crystalloid solution, urine volume, and length of hospital stay were lower/shorter in the experimental group than in the control group (P<0.05). Compared with the control group, the experimental group had higher MAP and lower HR (P<0.05). The first exhaust time, bowel sound recovery time, and time to eat in the experimental group were shorter than those in the control group (P<0.05). The total incidence of complications in the experimental group was significantly lower than that in the control group (10.4% vs. 28.6%, P<0.05).ConclusionTarget-directed liquid intervention is conducive to postoperative recovery and gastrointestinal function recovery in elderly patients with gastrointestinal tumors. In addition, it can help to improve hemodynamics and lower the occurrence risk of complications.

关 键 词：胃肠道肿瘤 老年人 目标导向液体干预 血流动力学 胃肠功能 

分 类 号：R735[医药卫生—肿瘤]