pMBRT:先进质子放射治疗技术基础与设计  

pMBRT:Principles and Design of Advanced Proton Radiotherapy Techniques

作　　者：王孝娃 杜宁 王岚 WANG Xiaowa;DU Ning;WANG Lan(Shanghai Proton and Heavy Ion Center,Shanghai,201321;Shanghai Key Laboratory of Radiation Oncology,Shanghai,201321;Shanghai Engineering Research Center of Proton and Heavy Ion Radiation Therapy,Shanghai,201321)

机构地区：[1]上海市质子重离子医院,上海市201321 [2]上海市放射肿瘤学重点实验室,上海市201321 [3]上海质子重离子放射治疗工程技术研究中心,上海市201321

出　　处：《中国医疗器械杂志》2024年第1期10-14,共5页Chinese Journal of Medical Instrumentation

摘　　要：该研究以先进的质子微束放射治疗(proton minibeam radiation therapy,pMBRT)为对象,介绍了pMBRT的发展历程、微束的生物学作用、微束保护组织的机理、微束的产生技术(准直器方法与磁聚焦方法)、质子微束矩阵阵列优缺点等,对pMBRT进行了综合的评价。提出将质子微束阵列与磁共振磁场结合,一方面有助于发挥pMBRT的正常组织保护功能,另一方面有助于提高质子治疗的精准性。The development history of pMBRT,the biological role of minibeam,the mechanism of minibeam protection of tissues,the generation of minibeam(collimator method and magnetic focusing method),and the analysis of advantages and disadvantages of proton minibeam matrix arrays is introduced with advanced proton minibeam arrays(pMBRT).It is proposed that the combination of proton minibeam arrays and magnetic resonance fields can help to exploit the normal tissue protective function of pMBRT,and improve the precision of proton therapy.

关 键 词：质子微束放射治疗 磁共振成像 剂量 质子阵列 

分 类 号：R730.55[医药卫生—肿瘤]