不同冲洗消毒的药物在根管治疗中对牙周牙髓病变的远期效果对比  

Comparison of long-term effects of different irrigation and disinfection drugs on periodontal-endodontic combined lesions in root canal therapy

作　　者：武利州 WU Li-zhou(Department of Stomatology,Longgang District Fifth People's Hospital,Shenzhen 518000,China)

机构地区：[1]深圳市龙岗区第五人民医院口腔科,518000

出　　处：《中国实用医药》2024年第2期53-56,共4页China Practical Medicine

基　　金：深圳市龙岗区经济与科技发展专项资金医疗卫生科技计划项目(项目编号:LGWJ2021-108)。

摘　　要：目的 分析不同冲洗消毒药物对根管治疗牙周牙髓联合病变的远期效果。方法 110例牙周牙髓联合病变患者,按照随机数字表法分为参照组与研究组,每组55例。所有患者均进行根管治疗,参照组辅以次氯酸钠溶液超声冲洗+氢氧化钙消毒,研究组辅以替硝唑溶液超声冲洗+盐酸米诺环素消毒。比较两组的牙周菌斑指数(PLI)、牙周袋深度(PD)、探诊出血指数(BI)、牙龈指数(GI)、临床附着水平(CAL)、疗效、复发率及牙齿松动、牙周炎、叩痛发生率。结果 研究组的治疗总有效率为96.36%,高于参照组的85.45%,差异具有统计学意义(P<0.05)。治疗后1、3个月,研究组的BI、PD、PLI、GI、CAL分别为(1.96±0.54)、(4.48±0.46)mm、(1.29±0.56)、(1.47±0.33)、(3.40±0.47)mm与(1.62±0.40)、(4.22±0.40)mm、(1.05±0.43)、(0.80±0.25)、(3.18±0.44)mm,均低于参照组的(2.30±0.52)、(4.90±0.53)mm、(1.68±0.49)、(1.69±0.31)、(3.83±0.52)mm与(1.93±0.47)、(4.87±0.47)mm、(1.33±0.40)、(1.23±0.27)、(3.65±0.46)mm,差异具有统计学意义(P<0.05)。治疗后6个月,研究组的PD(4.05±0.33)mm、CAL(3.10±0.38)mm低于参照组的(4.24±0.35)、(3.42±0.37)mm,差异具有统计学意义(P<0.05)。治疗后6个月,两组的BI、GI和PLI没有显著差异(P>0.05)。治疗后6个月,研究组的复发率3.64%、牙齿松动发生率1.82%、牙周炎发生率5.45%低于参照组的14.55%、12.73%、18.18%,差异具有统计学意义(P<0.05);两组的叩痛发生率没有显著差异(P>0.05)。结论 替硝唑溶液+米诺环素是合适的冲洗消毒药物,该方案具有良好的远期效果,能够改善牙周牙髓联合病变患者的牙周情况,预防疾病的复发。Objective To analyze the long-term effect of different irrigation and disinfection drugs on periodontal-endodontic combined lesions in root canal therapy.Methods 110 patients with periodontalendodontic combined lesions were divided into a reference group and a study group using random numerical table,with 55 cases in each group.All patients were treated with root canal therapy.The reference group was assisted by ultrasonic irrigation with sodium hypochlorite solution and disinfection with calcium hydroxide,while the study group was assisted by ultrasonic irrigation with tinidazole solution and disinfection with minocycline hydrochloride.Both groups were compared in terms of periodontal plaque index(PLI),periodontal pocket depth(PD),probing bleeding index(BI),gingival index(GI) and clinical attachment level(CAL),curative effect,recurrence rate,incidence of tooth looseness,periodontitis and percussion pain.Results The total effective rate of the study group was 96.36%,which was higher than that of 85.45% of the reference group,and the difference was statistically significant(P<0.05).At 1 month and 3 months after treatment,the BI,PD,PLI,GI and CAL in the study group were(1.96±0.54),(4.48±0.46) mm,(1.29±0.56),(1.47±0.33),(3.40±0.47) mm and(1.62±0.40),(4.22±0.40) mm,(1.05±0.43),(0.80±0.25),(3.18±0.44) mm,which were significantly lower than those of(2.30±0.52),(4.90±0.53) mm,(1.68±0.49),(1.69±0.31),(3.83±0.52) mm and(1.93±0.47),(4.87±0.47) mm,(1.33±0.40),(1.23±0.27),(3.65±0.46) mm in the reference group.The difference was statistically significant(P<0.05).At 6 months after treatment,PD of(4.05±0.33) mm and CAL of(3.10±0.38) mm in the study group were significantly lower than those of(4.24±0.35) and(3.42±0.37) mm in the reference group,and the difference was statistically significant(P<0.05).At 6 months after treatment,there were no significant differences in BI,GI and PLI between the two groups(P>0.05).At 6 months after treatment,the recurrence rate in the study group was 3.64%,the incidence of

关 键 词：牙周牙髓联合病变 替硝唑 米诺环素 消毒 复发 

分 类 号：R781.05[医药卫生—口腔医学]