Stem cell therapy:light in the tunnel for penetrating Crohn’s disease  

作　　者：Nan Lan Xianrui Wu Bo Shen 

机构地区：[1]Center for Inflammatory Bowel Disease,Columbia University Irving Medical Center/NewYork Presbyterian Hospital,New York,NY,USA [2]Department of Colorectal Surgery,The 6th Hospital of Sun Yat-Sen University,Guangzhou,Guangdong,P.R.China

出　　处：《Gastroenterology Report》2023年第1期78-87,共10页胃肠病学报道（英文）

摘　　要：Patients with Crohn’s disease frequently suffer from fistula resulting from adverse sequelae of persistent complicated active disease or surgical intervention.Fistula affects a patient’s quality of life and is directly associated with the need for surgical intervention.Diagnosis of fistula can be made through CT enterography,MR enterography,gastrograffin-based imaging,and transanal ultrasound.Treatment for fistula mainly consists of medication,endoscopic procedures,and surgery.There are emerging approaches under current investigation,such as stem cell therapy.The results showed a decent response in patients with perianal and rectovaginal fistula with minimal side effects.Further investigation is still needed for other internal fistula.

关 键 词：Crohn’s disease FISTULA perianal disease stem cells THERAPY 

分 类 号：R57[医药卫生—消化系统] R45[医药卫生—内科学]