CT引导下Hook-wire定位辅助胸腔镜手术对早期肺癌患者的疗效分析  

Effects of CT Guided Hook Wire Localization Assisted Thoracoscopy Surgery on Trauma Stress Indicators and Tumor Markers in Patients with Early Lung Cancer

作　　者：孔建峰[1] KONG Jianfeng(The First Affiliated Hospital of Zhengzhou University,Zhengzhou,450000)

机构地区：[1]郑州大学第一附属医院,450000

出　　处：《实用癌症杂志》2024年第2期255-258,共4页The Practical Journal of Cancer

摘　　要：目的探讨CT引导下Hook-wire定位辅助胸腔镜手术对早期肺癌患者的疗效。方法选取92例早期肺癌患者,按随机数字表法分为两组,各46例。对照组行常规胸腔镜手术治疗,观察组行CT引导下Hook-wire定位辅助胸腔镜手术治疗。比较两组手术情况、创伤应激指标、肿瘤标志物水平及并发症。结果观察组手术时间、术后引流时间及住院时间为(138.52±10.52)min、(3.12±0.45)d、(10.35±1.25)d,短于对照组,术中出血量为(105.41±12.36)ml,少于对照组,差异有统计学意义(P<0.05);观察组术后皮质醇(Cor)、去甲肾上腺素(NE)、C反应蛋白(CRP)水平分别为(118.52±8.36)ng/ml、(185.93±14.52)ng/L、(32.41±4.25)mg/L,低于对照组,差异有统计学意义(P<0.05);观察组术后癌胚抗原(CEA)、细胞角蛋白19片段抗原21-1(CYFRA21-1)、糖类抗原125(CA125)水平为(8.96±1.15)ng/ml、(3.88±0.42)ng/ml、(12.63±1.54)U/ml,低于对照组,并发症少于对照组,差异有统计学意义(P<0.05)。结论CT引导下Hook-wire定位辅助胸腔镜手术治疗早期肺癌效果更佳,可减轻手术创伤,降低创伤应激反应,加快肿瘤标志物复常,减少并发症发生。Objective To explore the effect of CT guided Hook wire localization assisted thoracoscopy surgery in early lung cancer patients.Methods 92 patients with early lung cancer were selected and randomly divided into 2 groups,with 46 patients in each group.The control group received routine thoracoscopy surgery,while the observation group received CT guided Hook wire localization assisted thoracoscopy surgery.Compare the surgical conditions,trauma stress indicators,tumor marker levels,and complications between the 2 groups.Results The surgical time,postoperative drainage time,and hospital stay in the observation group were(138.52±10.52)minutes,(3.12±0.45)days,and(10.35±1.25)days,which were shorter than those in the control group.The intraoperative bleeding volume was(105.41±12.36)ml,which was lower than that in the control group,and the difference was statistically significant(P<0.05);The postoperative levels of cortisol(Cor),Norepinephrine(NE)and C-reactive protein(CRP)in the observation group were(118.52±8.36)ng/ml,(185.93±14.52)ng/L and(32.41±4.25)mg/L,which were lower than those in the control group(P<0.05);The postoperative levels of Carcinoembryonic antigen(CEA),CYFRA21-1 and CA125 in the observation group were(8.96±1.15)ng/ml,(3.88±0.42)ng/ml and(12.63±1.54)U/ml,which were lower than those in the control group,and the complications were less than those in the control group,with statistical significance(P<0.05).Conclusion CT guided Hook wire localization assisted Thoracoscopy surgery is more effective in the treatment of early lung cancer,which can reduce the surgical trauma,reduce the traumatic stress reaction,speed up the recovery of tumor markers,and reduce complications.

关 键 词：早期肺癌 CT引导 Hook-wire定位 胸腔镜手术 创伤应激指标 肿瘤标志物 

分 类 号：R734.2[医药卫生—肿瘤]