老年肺癌患者术前气道定植菌及术后肺部并发症发生的相关因素研究  

A Study on the Related Factors of Preoperative Airway Colonization Bacteria and Postoperative Pulmonary Complications in Elderly Lung Cancer Patients

作　　者：牛丹丹 董永军 李海明 NIU Dandan;DONG Yongjun;LI Haiming(Zhumadian Central Hospital,Zhumadian,463000)

机构地区：[1]河南省驻马店市中心医院,463000

出　　处：《实用癌症杂志》2024年第2期263-266,共4页The Practical Journal of Cancer

摘　　要：目的探讨老年肺癌患者术前定植菌及术后肺部并发症发生的危险因素。方法回顾性分析80例老年肺癌患者的临床资料。所有患者术前均行气道定植菌筛查,依据是否存在气道定植菌分阳性组与阴性组,分析老年肺癌患者术前气道定植菌的危险因素;术后依据是否发生肺部并发症分为发生组与未发生组,分析影响老年肺癌患者术后肺部并发症的危险因素。结果80例老年肺癌患者中气道定植菌阳性率为37.50%(30/80),术后肺部并发症发生率为36.25%(29/80);单因素分析显示,SP-D、吸烟史与老年肺癌患者术前气道定植菌有关(P<0.05);多因素显示,SP-D<30 ng/ml、吸烟为影响老年肺癌术前气道定植菌的高危因素(P<0.05且OR>1);单因素显示,年龄、SP-D、吸烟史、气道定植菌、手术时间与老年肺癌术后肺部并发症的发生有关(P<0.05);多因素显示,年龄≥70岁、SP-D<30 ng/ml、吸烟、气道定植菌阳性、手术时间≥2 h为老年肺癌术后肺部并发症发生的高危因素(P<0.05且OR>1)。结论老年肺癌患者受SP-D<30 ng/ml、吸烟等影响,术前气道定植菌阳性较高,而年龄≥70岁、SP-D<30 ng/ml、吸烟、气道定植菌阳性、手术时间≥2 h为老年肺癌术后肺部并发症发生的高危因素,临床据此在围术期采取针对性干预措施,以降低术后肺部并发症风险。Objective To explore the risk factors for preoperative colonization of bacteria and postoperative pulmonary complications in elderly lung cancer patients.Methods A retrospective analysis was conducted on the clinical data of 80 elderly lung cancer patients.All patients underwent preoperative screening for airway colonization bacteria,and the risk factors for preoperative airway colonization bacteria in elderly lung cancer patients were analyzed based on the presence of positive and negative airway colonization bacteria;After surgery,patients were divided into 2 groups based on the occurrence of pulmonary complications:the occurrence group and the non occurrence group.The risk factors affecting postoperative pulmonary complications in elderly lung cancer patients were analyzed.Results The positive rate of airway colonization bacteria in 80 elderly lung cancer patients was 37.50%(30/80),and the incidence of postoperative pulmonary complications was 36.25%(29/80);Univariate analysis showed that SP-D and smoking history were associated with preoperative airway colonization bacteria in elderly lung cancer patients(P<0.05);Multivariate analysis showed that SP-D<30ng/ml and smoking were high-risk factors affecting preoperative airway colonization bacteria in elderly patients with lung cancer(P<0.05 and OR>1);Univariate analysis showed that age,SP-D,smoking history,airway colonization bacteria,and surgery time were associated with the occurrence of postoperative pulmonary complications in elderly patients with lung cancer(P<0.05);Multivariate analysis showed that age≥70 years,SP-D<30ng/ml,smoking,positive airway colonization bacteria,and surgery time≥2 hours were high-risk factors for postoperative pulmonary complications in elderly patients with lung cancer(P<0.05 and OR>1).Conclusion Elderly lung cancer patients are affected by factors such as SP-D<30ng/ml and smoking,and preoperative positive airway colonization bacteria are higher.However,age≥70 years,SP-D<30ng/ml,smoking,positive airway colonization bacteria,a

关 键 词：肺癌 手术 气道定植菌 肺部并发症 危险因素 

分 类 号：R734.2[医药卫生—肿瘤]