基于MRI及CT的双侧中线旁丘脑病灶体积错配比在丘脑肿瘤诊断中的价值  

Values of MRI-and CT-based volume mismatch ratios of bilateral paramedian thalamic lesions for discriminating thalamic tumors

作　　者：苏录[1] 周剑[1,2] 薛静[1,2] 高培毅[1,2] SU Lu;ZHOU Jian;XUE Jing;GAO Pei-yi(Department of Radiology,Beijing Tiantan Hospital,Capital Medical University,Beijing 100070,China;Neuroradiology Center of Beijing Neurosurgical Institute,Beijing 100070,China)

机构地区：[1]首都医科大学附属北京天坛医院放射科,北京100070 [2]北京市神经外科研究所神经影像中心,北京100070

出　　处：《医疗卫生装备》2023年第11期61-65,共5页Chinese Medical Equipment Journal

摘　　要：目的:探讨基于MRI及CT的双侧中线旁丘脑病灶体积错配比在丘脑肿瘤诊断中的价值。方法:回顾性分析某院2012年3月至2023年5月确诊的37例双侧中线旁丘脑肿瘤患者(肿瘤组)及36例非肿瘤患者(非肿瘤组)的病历资料。由2名观察者在MRI及CT图像上测量两侧病灶的前后径、左右径及上下径并计算其体积,再计算病灶体积较大侧与较小侧的体积错配比。采用组内相关系数(intra-class correlation efficient,ICC)比较2名观察者计算结果的一致性,采用t检验比较2组病灶体积错配比的差异,采用ROC曲线分析MRI及CT图像上双侧中线旁丘脑病灶体积错配比对丘脑肿瘤的诊断效能。采用SPSS 26.0软件进行统计学分析。结果:2名观察者计算的双侧中线旁丘脑病灶的体积错配比一致性好(ICC_(MRI)=0.910,P<0.001;ICC_(CT)=0.929,P<0.001)。肿瘤组病灶体积错配比均较非肿瘤组大,差异有统计学意义(t_(MRI)=2.621,P_(MRI)=0.011;t_(CT)=2.500,PCT=0.015)。ROC曲线分析显示,MRI及CT图像上双侧中线旁丘脑病灶体积错配比诊断肿瘤的AUC分别为0.788、0.749,诊断阈值分别为1.769、1.742,诊断敏感度分别为83.8%、70.3%,诊断特异度分别为77.8%、77.8%,Youden指数分别为61.6%、48.1%。结论:基于MRI及CT的双侧中线旁丘脑病灶体积错配比对丘脑肿瘤的诊断具有一定价值,CT相比MRI诊断效能略低,具有初筛价值。Objective To investigate the values of MRI-and CT-based volume mismatch ratios of bilateral paramedian thalamic lesions in the diagnosis of thalamic tumors.Methods The medical records of 37 patients with bilateral paramedian thalamic tumors(tumor group)and 36 non-tumor patients(non-tumor group)diagnosed from March 2012 to May 2023 in some hospital were analyzed retrospectively.The anteroposterior,left-right,and upper and lower diameters of the lesions on both sides were measured and their volumes were calculated on MRI and CT images by 2 observers,and the volume mismatch ratio between the two sides of the lesions was computed.Intra-class correlation efficiency(ICC)was used to explore the consistency of the calculation results between the two observers,the difference between the volume mismatch ratios of the two groups were compared with t-test,and the diagnostic efficacy of the volume mismatch ratio of bilateral paramedian thalamic lesions on MRI and CT images for diagnosing thalamic tumors was investigated with ROC curves.Statistical analysis was carried out with SPSS 26.0 software.Results The volume mismatch ratios of bilateral paramedian thalamic lesions calculated by the 2 observers were in good agreement(ICC_(MRI)=0.910,P<0.001;ICC_(CT)=0.929,P<0.001).The volume mismatch ratios of lesions in the tumor group were all higher than those in the non-tumor group,and the differences were statistically significant(t_(MRI)=2.621,P_(MRI)=0.011;t_(CT)=2.500,PCT=0.015).ROC curve analysis showed that the AUC values,diagnostic thresholds,diagnostic sensitivities and diagnostic specificities of the volume mismatch ratios of bilateral paramedian thalamic lesions on MRI and CT images for the diagnosis of thalamc tumors were 0.788 and 0.749,1.769 and 1.742,83.8%and 70.3%and 77.8%and 77.8%,respectively,and the Youden indices were 61.6%and 48.1%.Conclusion MRI-and CT-based volume mismatch ratios of bilateral paramedian thalamic lesions are of significane for the diagnosis of thalamic tumors,and CT behaves slightly worse than MR

关 键 词：双侧中线旁丘脑 MRI CT 体积错配比 丘脑肿瘤 

分 类 号：R739.41[医药卫生—肿瘤] R445.2[医药卫生—临床医学] R730.44