Polyneuropathy, organomegaly, endocrinopathy, M-protein, skin changes syndrome with dilated cardiomyopathy: A case report  

作　　者：Jia-Rong Li Lei-Yu Feng Jian-Wei Li Yu Liao Fei-Qi Liu 

机构地区：[1]Department of General Medicine,Xiangtan Central Hospital,Xiangtan 411100,Hunan Province,China

出　　处：《World Journal of Clinical Cases》2024年第3期601-606,共6页世界临床病例杂志

摘　　要：BACKGROUND Polyneuropathy,organomegaly,endocrinopathy,M-protein,skin changes(POEMS)syndrome is a rare paraneoplastic syndrome that encompass multiple systems.The most common clinical symptoms of POEMS syndrome are pro-gressive sensorimotor polyneuropathy,organ enlargement,endocrine disorders,darkening skin,a monoclonal plasma cell proliferative disorder,and lymph node hyperplasia.The organomegaly consists of hepatosplenomegaly and/or lym-phadenopathy;cases of cardiomyopathy are rare.Diagnoses are often delayed because of the atypical nature of the syndrome,exposing patients to possibly severe disability.Therefore,identifying atypical symptoms can improve the prognosis and quality of life among POEMS syndrome patients.lenalidomide and dexamethasone.CONCLUSION When patients with cardiomyopathy have systemic manifestations such as numb limbs and darkening skin,the POEMS syndrome is the most possible diagnosis.

关 键 词：POLYNEUROPATHY organomegaly ENDOCRINOPATHY M-PROTEIN skin changes syndrome Dilated cardiomyopathy LENALIDOMIDE Dexamethasone Case report 

分 类 号：R542.2[医药卫生—心血管疾病]