support from the National Natural Science Foundation of China(81972719,82273207).
Chronic inflammatory demyelinating polyneuropathy(CIDP)is a rare immune-mediated disease characterized by refractory and relapsed peripheral nerve and nerve root damage,leading to severe sequelae for patients.Although...
Intensive care unit-acquired weakness(ICU-AW;ICD-10 Code:G72.81)is a syndrome of generalized weakness described as clinically detectable weakness in critically ill patients with no other credible cause.The risk factor...
BACKGROUND Polyneuropathy,organomegaly,endocrinopathy,M-protein,skin changes(POEMS)syndrome is a rare paraneoplastic syndrome that encompass multiple systems.The most common clinical symptoms of POEMS syndrome are pro...
Objective Chinese herbal medicine(CHM)has been commonly used in Distal Symmetric Polyneuropathy(DSPN)treatment with satisfactory clinical effects,but the underlying pharmacological mechanism of CHM on DSPN remains unc...
BACKGROUND Polyneuropathy organomegaly endocrinopathy M-protein and skin changes(POEMS)syndrome is a rare paraneoplastic syndrome caused by a potential plasma cell tumor.The clinical manifestations of POEMS syndrome a...
Pharmaceuticals targeting the pathogenesis of diabetic distal symmetric polyneuropathy have all failed in clinical trials, limiting recourse to palliative treatments. The American Diabetes Association regards the effe...
This work was partly supported by Grants-in-Aid for Scientific Research(61480439,63440082,10470506,13470509,17200028 to K.Y.,21590361,24590404,19K07354 to Z.L.)from the Japan Society for the Promotion of Science.The manuscript has been carefully edited by Nature Research Editing Service(http://authorservices.springernature.com).
Familial amyloidotic polyneuropathy(FAP)is a type of systemic amyloidosis characterized by peripheral and autonomic neuropathy.Although FAP is a typical autosomal dominant disorder caused by a point mutation in the TT...
Background: The condition known as polyneuropathy causes peripheral nerve disability, and is characterized by symmetrical distal numbness and paresthesia, often accompanied by pain and weakness. With the advancement o...
BACKGROUND Polyneuropathy,organomegaly,endocrinopathy,M-protein,and skin changes(POEMS)syndrome is a rare paraneoplastic syndrome caused by a plasma cell proliferative disorder.The syndrome is characterized by elevate...
Neuromuscular ultrasound(NMUS) is a rapidly evolving technique used in neuromuscular medicine to provide complimentary information to standard electrodiagnostic studies. NMUS provides a dynamic, real time assessment o...