乳腺癌标志物与女性乳腺癌放化疗敏感性关系的研究进展  

Research Progress in Relationship between Breast Cancer Markers and Radiochemotherapy Sensitivity in Female Breast Cancer

作　　者：刘雨佳 张英 李丽霞 LIU Yujia;ZHANG Ying;LI Lixia(Department of Breast and Esophagus Medicine,Affiliated Hospital of Guangdong Medical University,Zhanjiang 524000,China)

机构地区：[1]广东医科大学附属医院乳腺食管专科,广东湛江524000

出　　处：《医学综述》2024年第3期316-320,共5页Medical Recapitulate

摘　　要：乳腺癌是一种严重威胁女性健康的恶性肿瘤。近年随着研究技术的发展,乳腺癌的治疗方案已取得一定进展,但放化疗的疗效仍是影响乳腺癌患者生存的重要因素。乳腺癌标志物(Ki-67、p53、ATP结合盒式蛋白G2、环加氧酶)在疾病诊断、疗效及预后评估中具有重要临床意义,可反映肿瘤细胞及组织的某些特性。因此,深入研究乳腺癌标志物与女性乳腺癌放化疗敏感性的相关性,可全面了解乳腺癌标志物在女性乳腺癌放化疗中的作用,为乳腺癌的临床治疗提供新思路。Breast cancer is a malignancy with a serious threat to women′s health.In recent years,with the development of research technology,the treatment of breast cancer has made some progress,but the efficacy of radiotherapy and chemotherapy is still an important factor affecting the survival of the patients.Breast cancer markers(Ki-67,p53,ATP-binding cassette transporter G2 and cyclooxygenase)have important clinical significance in the diagnosis,efficacy and prognosis evaluation of the disease,and can reflect some characteristics of tumor cells and tissues.Therefore,in-depth study of the correlation of breast cancer markers with radiochemotherapy sensitivity of female breast cancer can help to comprehensively understand their roles in the radiochemotherapy,and provide new ideas for the clinical treatment of breast cancer.

关 键 词：乳腺癌 生物标志物 放化疗敏感性 

分 类 号：R737.9[医药卫生—肿瘤]