数字乳腺断层摄影评估新辅助化疗后肿瘤大小的价值  

Value of digital breast tomosynthesis in evaluating tumor size after neoadjuvant chemotherapy

作　　者：赵爱丽[1] 逯兆喜 裴彩英[1] 李峰[1] 吴超 ZHAO Aili;LU Zhaoxi;PEI Caiying;LI Feng;WU Chao(Liaocheng People's Hospital,Liaocheng 252000;Liaocheng Tumor Hospital,Liaocheng 252000,China)

机构地区：[1]聊城市人民医院,山东聊城252000 [2]聊城市肿瘤医院,山东聊城252000

出　　处：《临床医学研究与实践》2024年第5期88-91,共4页Clinical Research and Practice

摘　　要：目的评估新辅助化疗后数字乳腺断层摄影(DBT)、全数字化乳腺摄影(FFDM)和超声(US)检查预测残留肿瘤大小的能力。方法回顾性分析2020年1月1日至2021年12月31日病理结果确诊为乳腺癌,行新辅助化疗并接受手术治疗患者的临床及影像学资料。所有患者在新辅助化疗后均行乳腺DBT、FFDM及US检查。采用Pearson相关分析计算不同影像检查方法测量残留肿瘤大小与病理测量结果的相关性;以0.5 cm为阈值,分析不同影像检查预测残留肿瘤大小的准确率。结果85例患者,共86个病灶,去除新辅助化疗后无残留癌的病灶,共纳入72个病灶。新辅助化疗后,DBT、FFDM、US测量残留肿瘤大小与病理测量结果均呈中等程度相关。DBT、FFDM、US预测残留肿瘤大小的准确率分别为59.72%(43/72)、43.06%(31/72)、41.67%(30/72)。DBT与FFDM、US预测残留肿瘤大小的准确率比较,差异具有统计学意义(χ^(2)=4.003、4.695,P=0.045、0.030)。结论新辅助化疗后,DBT预测残留肿瘤大小的准确率优于FFDM与US。DBT在新辅助化疗后的术前评估具有良好的应用前景。Objective To evaluate the ability of digital breast tomosynthesis(DBT),full-field digital mammography(FFDM)and ultrasound(US)to predict residual tumor size after neoadjuvant chemotherapy.Methods The clinical and imaging data of patients who were diagnosed as breast cancer by pathological findings and received neoadjuvant chemotherapy and surgery from January 1,2020 to December 31,2021 were analyzed retrospectively.All patients underwent breast DBT,FFDM and US examinations after neoadjuvant chemotherapy.Pearson correlation analysis was used to calculate the correlation between residual tumor size measured by different imaging methods and pathological measurement results;the accuracy of different imaging examinations in predicting residual tumor size was analyzed with 0.5 cm as the threshold.Results A total of 86 lesions were included in 85 patients,and 72 lesions were included after removing the lesions without residual cancer after neoadjuvant chemotherapy.After neoadjuvant chemotherapy,the residual tumor size measured by DBT,FFDM and US was moderately correlated with the pathological measurement results.The accuracy of DBT,FFDM and US in predicting residual tumor size was 59.72%(43/72),43.06%(31/72)and 41.67%(30/72),respectively.The accuracy of DBT in predicting residual tumor size was significantly different from that of FFDM and US(χ^(2)=4.003,4.695;P=0.045,0.030).Conclusion After neoadjuvant chemotherapy,the accuracy of DBT in predicting residual tumor size is better than that of FFDM and US.DBT has a good application prospect in preoperative evaluation after neoadjuvant chemotherapy.

关 键 词：乳腺癌 数字乳腺断层摄影 全数字化乳腺摄影 超声 新辅助化疗 

分 类 号：R730.53[医药卫生—肿瘤]