老年食管癌患者术后反流性食管炎的影响因素  

Influential Factors of Reflux Esophagitis in Elderly Patients with Esophageal Cancer After Surgery

作　　者：李悦华 吴倩 郭亚杰 LI Yuehua;WU Qian;GUO Yajie(Thoracic Surgery,Zhengzhou University Affiliated Cancer Hospital(Henan Cancer Hospital),Zhengzhou 450000,China)

机构地区：[1]郑州大学附属肿瘤医院(河南省肿瘤医院)胸外科,河南郑州450000

出　　处：《河南医学研究》2024年第2期233-236,共4页Henan Medical Research

摘　　要：目的探讨老年食管癌患者术后发生反流性食管炎的影响因素。方法选取医院2018年7月至2021年5月收治的154例老年食管癌根治术患者为研究对象,根据是否并发反流性食管炎分组,采用单因素及logistic回归模型分析相关指标与老年食管癌根治术后发生反流性食管炎关系,并制定针对性干预措施。结果154例老年食管癌根治术患者有44例(28.57%)发生反流性食管炎。两组吸烟史、体重指数(BMI)、饮酒史、血糖水平、白蛋白水平、消化道重建方式、汉密尔顿焦虑量表(HAMA)、汉密尔顿抑郁量表(HAMD)评分差异有统计学意义(P<0.05)。BMI、吸烟史、血糖水平、消化道重建方式、HAMA评分、HAMD评分是诱发反流性食管炎影响因素。结论老年食管癌根治术后反流性食管炎发生风险较高,主要与BMI、吸烟史、血糖水平、消化道重建方式、HAMA评分、HAMD评分有关,临床应重视具有上述风险因素患者的早期合理干预,以降低反流性食管炎发生风险,改善预后。Objective To investigate the risk factors of reflux esophagitis in elderly patients with esophageal cancer after surgery.Methods A total of 154 elderly patients with esophageal cancer who underwent radical surgery in the hospital from July 2018 to May 2021 were selected as the research subjects.They were grouped based on whether they developed reflux esophagitis.Univariate and logistic regression models were used to analyze the relationship between relevant indicators and the occurrence of reflux esophagitis after radical surgery in elderly esophageal cancer patients,and targeted intervention measures were formulated.Results There were 44 out of 154(28.57%)elderly patients with esophageal cancer undergoing radical surgery developed reflux esophagitis.There were statistical differences in smoking history,body mass index(BMI),alcohol consumption history,blood glucose level,albumin level,digestive tract reconstruction method,Hamilton anxiety scale(HAMA),and Hamilton depression scale(HAMD)scores between the two groups(P<0.05).BMI,smoking history,blood glucose level,digestive remodeling mode,HAMA score and HAMD score were the influencing factors of induced reflux esophagitis.Conclusion The risk of reflux esophagitis in elderly patients after radical resection of esophageal cancer is higher,which is mainly related to BMI,smoking history,blood glucose level,digestive tract reconstruction mode,HAMA score,HAMD score.

关 键 词：食管癌 食管癌根治术 反流性食管炎 影响因素 

分 类 号：R735.1[医药卫生—肿瘤]