^(125)I放射性支架用于晚期食管癌恶性狭窄的治疗进展  

Progress in the treatment of malignant stenosis of advanced esophageal cancer with^(125)I radioactive stents

作　　者：李瑞卿 蒋马伟[1] 郑磊贞[1] Li Ruiqing;Jiang Mawei;Zheng Leizhen(Department of Oncology,Xinhua Hospital Affiliated to Shanghai Jiao Tong University,Shanghai 200092,China)

机构地区：[1]上海交通大学医学院附属新华医院肿瘤科,上海200092

出　　处：《中华放射肿瘤学杂志》2024年第2期173-177,共5页Chinese Journal of Radiation Oncology

基　　金：国家自然科学基金面上项目(81974368)。

摘　　要：食管癌是中国最常见的恶性肿瘤之一。恶性狭窄导致的吞咽困难是晚期食管癌最常见的症状,无法经口进食严重影响晚期食管癌患者的生活质量,其所引起的营养不良状况也限制了放、化疗等标准治疗方案的实施,进而导致生存率下降。^(125)I粒子放射性支架是一种新颖的治疗恶性狭窄的方式,研究表明其相较于传统食管支架可更好地缓解吞咽困难并延长患者生存期。本文就晚期食管癌恶性狭窄的治疗、^(125)I粒子放射性支架的临床应用进展展开综述。Esophageal cancer is one of the most common malignant tumors in China and dysphagia caused by malignant stenosis is the most common symptom of advanced esophageal cancer.The inability to eat orally seriously affects the quality of life of patients with advanced esophageal cancer,and poor nutritional status caused by dysphagia limits the implementation of standard treatment programs such as radiotherapy and chemotherapy,resulting in a decline in survival.The^(125)I radioactive stent is a novel treatment for malignant stenosis.Studies have shown that it can relieve dysphagia and prolong patients'survival compared to traditional esophageal stents.In this article,the treatment of malignant stenosis in advanced esophageal cancer and the clinical application progress of^(125)I radioactive stents were reviewed.

关 键 词：食管肿瘤 ^(125)I放射性支架 吞咽障碍 恶性狭窄 进展 

分 类 号：R735.1[医药卫生—肿瘤]