脑灰质异位相关癫痫^(18)F-FDG PET/MRI表现  

^(18)F-FDG PET/MRI manifestations of gray matter heterotopia related to epilepsy

作　　者：黎颖昕 凌雪英[1] 唐勇进[1] 程勇[1] 徐浩[1] LI Yingxin;LING Xueying;TANG Yongjin;CHENG Yong;XU Hao(Department of Nuclear Medicine,the First Affiliated Hospital of Jinan University,Guangzhou 510630,China)

机构地区：[1]暨南大学附属第一医院核医学科,广东广州510630

出　　处：《中国医学影像技术》2024年第2期203-207,共5页Chinese Journal of Medical Imaging Technology

摘　　要：目的观察脑灰质异位(GMH)相关癫痫的18 F-FDG PET/MRI表现。方法回顾性分析27例经MRI诊断GMH癫痫患者,观察其颅脑18 F-FDG PET/MRI表现、有无其他颅脑畸形并进行分型。结果27例中,15例室管膜下GMH、2例皮质下GMH、2例层状(带状)GMH、8例混合型GMH;相比病灶周围或对侧镜像区脑白质,22例糖代谢增高、3例糖代谢减低,2例糖代谢未见明显异常;相比中央前回灰质,8例糖代谢增高、16例糖代谢减低,3例糖代谢未见明显异常。27例中,6例合并脑裂畸形,6例合并双侧小脑半球体积缩小,合并透明隔缺如及穹隆低位、胼胝体发育异常、多微小脑回畸形各1例。结论GMH相关癫痫18 F-FDG PET/MRI表现具有一定特征性,有助于临床诊断。Objective To observe^(18)F-FDG PET/MRI manifestations of gray matter heterotopia(GMH)related epilepsy.Methods Data of 27 patients with GMH and epilepsy diagnosed with MRI were retrospectively analyzed.Brain^(18)F-FDG PET/MRI manifestations and complicated brain malformations were observed,and the classification of GMH were performed.Results Among 27 cases,periventricular GMH,focal subcortical GMH,subcortical lamellar(band)GMH and mixed GMH were detected each in 15,2,2 and 8 cases,respectively.Compared with cerebral white matter around the lesion or in the contralateral mirror area of the lesion,glucose hypermetabolism and glucose hypometabolism were found in 22 and 3 cases,respectively,while glucose metabolism was normal in 2 cases.Compared with gray matter in precentral gyrus,glucose hypermetabolism and glucose hypometabolism were observed in 8 and 16 cases,respectively,while glucose metabolism was normal in 3 cases.Six cases complicated with cerebral fissure deformity,6 cases with bilateral cerebellar hemispheric volume reduction,1 case with absence of pellucid septum and lower fornix,1 case with dysplasia of corpus callosum and 1 case with polymicrogyria.Conclusion^(18)F-FDG PET/MRI manifestations of GMH related epilepsy had certain characteristics,which were helpful for clinical diagnosis.

关 键 词：神经系统畸形 脑灰质 癫痫 正电子发射断层显像 磁共振成像 

分 类 号：R742[医药卫生—神经病学与精神病学] R817[医药卫生—临床医学]