前列腺混合性癌行机器人辅助根治性前列腺切除术后穿刺孔转移1例报告  

A case report of trocar-site metastasis after robot-assisted laparoscopic radical prostatectomy

作　　者：赵迪威 安欣[2] 曹云 周芳坚[1] 李永红[1] Zhao Diwei;An Xin;Cao Yun;Zhou Fangjian;Li Yonghong(Department of Urology,Sun Yat-sen University Cancer Center,State Key Laboratory of Oncology in South China,Collabrative Innovation Center for Cancer Medicine,Guangzhou 510060,China;Department of Medical Oncology,Sun Yat-sen University Cancer Center,State Key Laboratory of Oncology in South China,Collabrative Innovation Center for Cancer Medicine,Guangzhou 510060,China;Department of Pathology,Sun Yat-sen University Cancer Center,State Key Laboratory of Oncology in South China,Collabrative Innovation Center for Cancer Medicine,Guangzhou 510060,China)

机构地区：[1]中山大学肿瘤防治中心泌尿外科、华南肿瘤学国家重点实验室、肿瘤医学协同创新中心,广州510060 [2]中山大学肿瘤防治中心肿瘤内科、华南肿瘤学国家重点实验室、肿瘤医学协同创新中心,广州510060 [3]中山大学肿瘤防治中心病理科、华南肿瘤学国家重点实验室、肿瘤医学协同创新中心,广州510060

出　　处：《中华泌尿外科杂志》2024年第1期61-62,共2页Chinese Journal of Urology

摘　　要：前列腺癌种植转移罕见。本文报道1例前列腺混合性癌,于外院行前列腺穿刺活检示前列腺腺泡腺癌,行机器人辅助腹腔镜根治性前列腺切除术,术后病理示前列腺混合性癌,小细胞癌为主。术后5个月于外院发现穿刺孔转移。于我院行化疗联合免疫治疗6个周期,维持药物去势及免疫治疗。化疗结束后3个月,影像学检查评估肿瘤完全缓解。免疫治疗维持治疗10个月后因不良反应停药。免疫治疗停药后15个月肿瘤无进展生存。Tumor seeding is rare in prostate cancer.We reported a case of trocar-site metastasis detected at 5 months after robot-assisted laparoscopic radical prostatectomy in a prostate cancer patient with a mixed histology of small cell carcinoma and adenocarcinoma.The patient received 6 cycles of a combination of chemotherapy and immunotherapy and a maintenance regimen of androgen deprivation therapy and immunotherapy at our center.The maintenance of immunotherapy suspended at 10 months after the first dosage due to adverse effect.Three months after the end of chemotherapy,imaging evaluation showed that the tumor had achieved complete remission.Tumor relapse was not detected at 15 months after the suspension of immunotherapy.

关 键 词：前列腺肿瘤 小细胞癌 种植转移 根治性前列腺切除术 

分 类 号：R737.25[医药卫生—肿瘤]