2013—2018年山东省肿瘤登记地区肺癌发病与死亡趋势分析  

Lung cancer mortality trend in cancer registration areas of Shandong Province from 2013 to 2018

作　　者：田新宇 任杰[2] 周亚霖 徐春晓[2] 姜帆 鹿子龙[2] 郭晓雷[2] 付振涛[2] 马吉祥[3] TIAN Xinyu;REN Jie;ZHOU Yalin;XU Chunxiao;JIANG Fan;LU Zilong;GUO Xiaolei;FU Zhentao;MA Jixiang(School of Public Health,Weifang Medical University,Weifang,Shandong Province 261053,China;不详)

机构地区：[1]潍坊医学院公共卫生学院,山东省潍坊261053 [2]山东省疾病预防控制中心慢病所,山东省济南250014 [3]山东省疾病预防控制中心,山东省济南250014

出　　处：《中国慢性病预防与控制》2023年第11期842-846,共5页Chinese Journal of Prevention and Control of Chronic Diseases

基　　金：山东省医药卫生科技发展计划(202012051127);国家重点研发计划精准医学重点研究专项(2016YFC0901300);山东省重点研发计划(2016GSF201231);泰山学者工程专项(ts201511105)。

摘　　要：目的了解2013—2018年山东省肿瘤登记地区肺癌发病和死亡现状,为后期肺癌防治提供参考依据。方法数据来源于山东省肿瘤登记数据库,提取2013—2018年肺癌发病和死亡数据进行分析。用Excel 2010和SAS 9.4软件计算发病(死亡)率、标化率和0~74岁累积率等,不同性别、城乡间比较采用Z检验。采用Joinpoint 4.8.0.1软件进行发病率和死亡率的变化趋势分析,计算年度变化百分比(APC)。结果2018年山东省肿瘤登记地区肺癌粗发病率为78.15/10万,中标发病率为42.56/10万,肺癌粗死亡率为57.04/10万,中标死亡率为29.77/10万。2018年山东省肺癌年龄别发病率和死亡率随着年龄增长而上升,分别在80~84岁和85岁及以上年龄组达到最高峰。2018年山东省肿瘤登记地区肺癌发病死亡均存在性别差异,男性中标发病率为女性的1.79倍,中标死亡率为女性的2.37倍。2013—2018年山东省肿瘤登记地区肺癌粗发病率呈上升趋势,有统计学意义(APC=2.53%,P<0.05),而中标发病率的变化趋势无统计学意义(P>0.05);肺癌粗死亡率的变化趋势无统计学意义(P>0.05),死亡中标率呈下降趋势(APC=-3.09%,P<0.05)。结论山东省肿瘤登记地区肺癌总体发病呈现上升趋势,男性与老年人仍为主要高危人群,山东省肺癌防控形势严峻,应采取相应防控措施,降低肺癌疾病负担。Objective To understand the incidence and mortality status of lung cancer in cancer registration areas of Shandong Province from 2013 to 2018,and provide the reference basis for the prevention and treatment of lung cancer in the future.Methods Data were from the Shandong Cancer Registry Database,and the incidence and mortality data of lung cancer from 2013 to 2018 were extracted for analysis.Excel 2010 and SAS 9.4 were used to calculate the incidence(mortality),standardized rate,and cumulative rate(0-74 years old),etc.The Z test was used to compare the differences between different genders and urbanrural areas.Joinpoint 4.8.0.1 software was used for trend analysis of the incidence and mortality,and the annual percent change(APC)was calculated.Results The crude morbidity of lung cancer in cancer registration areas of Shandong Province in 2018 was 78.15/105,and the age-standardized morbidity was 42.56/105.The crude mortality of lung cancer was 57.04/105,and the agestandardized mortality was 29.77/105.The age-specific incidence and mortality of lung cancer in Shandong Province in 2018 increased with age,reaching their peak in the 80-84 ages group and the≥85 years old group.There were gender differences of incidence and mortality of lung cancer in the registered areas of Shandong Province in 2018,the male age-standardized incidence is 1.79 times as high as that of females;and the male age-standardized mortality is 2.37 times as high as that of females.From 2013 to 2018,the crude incidence of lung cancer in the registered areas of Shandong Province showed the significant upward trend(APC=2.53%,P<0.05),while the trend in age-standardized incidence rate was not statistically significant(P>0.05).The trend in crude mortality of lung cancer was not statistically significant(P>0.05),while the age-standardized mortality showed the decreasing trend(APC=-3.09%,P<0.05).Conclusion The overall incidence of lung cancer in the cancer registration area of Shandong Province shows the upward trend.Men and the elderly remain the main

关 键 词：肺癌 发病率 死亡率 肿瘤登记 

分 类 号：R734.2[医药卫生—肿瘤]