胆汁反流性胃炎胃镜检查表现及铝碳酸镁的治疗效果研究  

Endoscopic manifestations of bile reflux gastritis and the therapeutic effects of aluminum hydroxide and magnesium carbonate:a study

作　　者：赵来峰 吴正卿 贾琼 ZHAO Laifeng;WU Zhengqing;JIA Qion(Department of Spleen-Stomach-Liver-Gallbladder,Qingyang Traditional Chinese Medicine Hospital,Gansu Province,Qingyang,Gansu,745000,Chin)

机构地区：[1]甘肃省庆阳市中医医院脾胃肝胆科,甘肃庆阳745000

出　　处：《中国冶金工业医学杂志》2024年第1期1-2,共2页Chinese Medical Journal of Metallurgical industry

摘　　要：目的分析胆汁反流性胃炎的胃镜检查表现,同时探究铝碳酸镁对其的治疗效果。方法选取2021年2—12月于本院治疗的88例胆汁反流性胃炎患者。根据治疗方法不同将其分为参考组与研究组,每组各44例。参考组给予多潘立酮治疗,研究组在参考组基础上加用铝碳酸镁治疗。分析胃镜检查表现,对比两组治疗总有效率、胃内吸出物水平、生活质量及不良反应情况。结果研究组治疗总有效率高于参考组,两组比较差异有统计学意义(χ^(2)=5.091,P<0.05);研究组胃酸分泌量与胃液胆酸量均低于参考组,各生活质量评分均高于参考组,两组比较差异均有统计学意义(t=8.533、23.239、8.108、13.883、9.655、10.479,均P<0.05);而两组不良反应发生率比较,差异无统计学意义(χ^(2)=0.138,P>0.05)。结论胃镜检查可对胆汁反流性胃炎进行有效诊断,而铝碳酸镁在治疗胆汁反流性胃炎患者中的疗效显著,且用药安全性良好。Objective To analyze the gastroscopic manifestations of bile reflux gastritis and nvestigate the therapeutic effect of aluminum hydroxide and magnesium carbonate on the condition.Methods A total of 88 patients with bile reflux gastritis treated in our hospital from February to December 2021 were selected.According to different treatment plans,they were divided into a reference group and a research group,with 44 patients in each group.The patients in the reference group was treated with domperidone,while in the research group received additional treatment with aluminum hydroxide and magnesium carbonate.Gastroscopic manifestations were analyzed,and the overall treatment effectiveness,gastric aspirate levels,quality of life,and adverse reactions were compared between the two groups.Results The overall treatment effectiveness in the research group was higher than that in the reference group,and the difference was statistically significant(χ^(2)=5.091,P<0.05).The gastric acid secretion and bile acid levels in the gastric fluid of the research group were both lower than those in the reference group,and all quality-of-life scores were higher than in the reference group.The differences between the two groups were statistically significant(t=8.533,23.239,8.108,13.883,9.655,10.479,all P<0.05).However,there was no significant difference in the incidence of adverse reactions between the two groups(χ^(2)=0.138,P>0.05).Conclusion Gastroscopy can effectively diagnose bile reflux gastritis.Aluminum hydroxide and magnesium carbonate have shown remarkable therapeutic effects in treating patients with bile reflux gastritis,with good medication safety.

关 键 词：胆汁反流性胃炎 胃镜诊断 铝碳酸镁 多潘立酮 

分 类 号：R573[医药卫生—消化系统]