经皮穴位电刺激在酒精依赖患者中的应用效果  

Effect of transcutaneous electrical stimulation of acupoints in patients with alcohol dependence

作　　者：谢婷 侯超[1] 周旭辉[1] 郭育君[1] 练宇泽 曾亚琦 XIE Ting;HOU Chao;ZHOU Xuhui;GUO Yujun;LIAN Yuze;ZENG Yaqi(Department of Psychiatry,Hunan Provincial Brain Hospital,Hunan Second People′s Hospital,Changsha,Hunan,410007)

机构地区：[1]湖南省脑科医院/湖南省第二人民医院精神科,湖南长沙410007

出　　处：《实用临床医药杂志》2024年第2期38-42,共5页Journal of Clinical Medicine in Practice

基　　金：湖南省自然科学基金科卫联合项目(2021JJ70089);湖南省卫生健康委科研计划项目(202103092373)。

摘　　要：目的观察经皮穴位电刺激在酒精依赖患者心理渴求和稽延性戒断症状中的应用效果。方法选取在湖南省脑科医院酒瘾科住院的120例酒精依赖完成急性脱瘾期的男性患者为研究对象,根据患者治疗方式的不同分为常规药物组、经皮穴位电刺激组及假刺激组,每组40例。常规药物组采用苯二氮[艹卓]类药物替代递减以及支持性对症治疗,经皮穴位电刺激组采用常规治疗联合经皮穴位电刺激,假刺激组采用常规治疗联合模拟经皮穴位电刺激。比较3组患者治疗前后焦虑自评量表(SAS)评分及抑郁自评量表(SDS)评分、饮酒迫切性量表(AUQ)评分、视觉模拟评分法(VAS)评分、匹兹堡睡眠质量指数(PSQI)评分及复发情况。结果治疗后,3组患者SAS、SDS、AUQ及VAS评分均较治疗前降低,且经皮穴位电刺激组以上评分均低于常规药物组及假刺激组,差异有统计学意义(P<0.05)。治疗后,3组患者睡眠质量、入睡时间、睡眠时间、睡眠效率、睡眠障碍、催眠药物、日间功能障碍评分及PSQI总分均低于治疗前,且经皮穴位电刺激组以上评分均低于常规药物组及假刺激组,差异有统计学意义(P<0.05)。经皮穴位电刺激组复发率低于常规药物组及假刺激组,差异有统计学意义(P<0.05)。结论相较于常规治疗及模拟经皮电刺激,经皮穴位电刺激治疗更有利于减轻患者焦虑、抑郁及失眠等稽延性戒断症状严重程度,并利于降低患者心理渴求程度,从而降低复发率。Objective To observe the application effect of transcutaneous acupoint electrical stimulation in the psychological craving and protracted abstinence symptoms of alcohol-dependent patients.Methods A total of 120 male alcohol-dependent patients who completed the acute alcohol withdrawal phase and were hospitalized in the Department of Alcoholism in Hunan Brain Hospital were selected as the study subjects.They were divided into conventional drug group,transcutaneous acupoint electrical stimulation group and placebo group according to different treatment methods,with 40 patients in each group.The conventional drug group was treated with benzodiazepine drugs for replacement and reduction and supportive symptomatic treatment.The transcutaneous acupoint electrical stimulation group was treated with conventional treatment combined with transcutaneous acupoint electrical stimulation.The placebo group was treated with conventional treatment combined with simulated transcutaneous acupoint electrical stimulation.The Self-rating Anxiety Scale(SAS),Self-rating Depression Scale(SDS),Alcohol Urge Questionnaire(AUQ),Visual Analogue Scale(VAS),Pittsburgh Sleep Quality Index(PSQI)score and recurrence conditions were compared before and after treatment among the three groups.Results After treatment,the SAS,SDS,AUQ and VAS scores of the three groups were lower than those before treatment,and the above scores of the transcutaneous acupoint electrical stimulation group were lower than those of the conventional drug group and placebo group(P<0.05).After treatment,the scores of sleep quality,the time to fall asleep,sleep duration,sleep efficiency,sleep disturbance,hypnotic drugs,daytime dysfunction and total PSQI score of the three groups were lower than those before treatment,and the above scores of the transcutaneous acupoint electrical stimulation group were lower than those of the conventional drug group and placebo group(P<0.05).The recurrence rate of the transcutaneous acupoint electrical stimulation group was lower than that of th

关 键 词：经皮穴位电刺激 酒精依赖 心理渴求 稽延性戒断症 复发 

分 类 号：R749.053[医药卫生—神经病学与精神病学] R473.74[医药卫生—临床医学] R245.9