Current perspective on amyloid aggregation accelerating properties of the artificial butter flavoring,diacetyl  

作　　者：Ashish P.Vartak Swati S.More 

机构地区：[1]Center for Drug Design,College of Pharmacy,University of Minnesota,Minneapolis,MN,USA

出　　处：《Neural Regeneration Research》2024年第10期2113-2114,共2页中国神经再生研究（英文版）

基　　金：supported by the National Institutes of Health Grant (R01-AG062469);the Grantin-Aid of Research,Artistry,Scholarship program (GIA,Project 143977) at the University of Minnesota;funding from the Center for Drug Design (CDD),University of Minnesota (to SSM)。

摘　　要：The amyloid—what peptide can resist its entropic bliss?Without kinetic barricades and chaperones,most peptides would simply tumble down that precipice.The amyloid-β(Aβ) peptides are understood to underlie the hallmark pathology of Alzheimer's disease(AD) and are considered one of the causative factors for neurodegeneration and cognitive impairment.AD affects critical connected structures within the brain that are responsible for memory,language,and social behavior.

关 键 词：AMYLOID ALZHEIMER AΒ 

分 类 号：R338[医药卫生—人体生理学]