基于CiteSpace和VOSviewer脑出血自噬研究的可视化分析  

Visualization Analysis of Autophagy in Intracerebral Hemorrhage Based on CiteSpace and VOSviewer

作　　者：高玉广[1] 钟洁[1] 黄德庆[1] 邓海霞[1] 刘永辉[1] 张元侃[1] 刘泰[1] GAO Yuguang;ZHONG Jie;HUANG Deqing;DENG Haixia;LIU Yonghui;ZHANG Yuankan;LIU Tai(The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine,Nanning 530023,Guangxi,China)

机构地区：[1]广西中医药大学第一附属医院,南宁530023

出　　处：《中西医结合心脑血管病杂志》2024年第4期614-620,共7页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：广西壮族自治区教育厅高校中青年教师科研基础能力提升项目(No.2020KY07015);广西壮族自治区中医药管理局自筹经费科研课题(No.GZZC2020036);第七批全国老中医药专家学术经验继承工作项目,编号:国中医药人教函[2022]76号;广西名中医(刘泰)传承工作室建设项目,编号:桂中医药科教发[2021]6号;广西中医药优秀人才培养项目,编号:桂中医药科教发[2022]14号。

摘　　要：目的:对脑出血自噬的文献进行可视化解读和分析,探讨脑出血自噬研究动态和趋势。方法:检索1991年1月1日—2022年12月1日中国知网发表的脑出血自噬研究的相关文献。采用CiteSpace和VOSviewer软件分析检索获得文献的作者、主题、来源分布、数量等并进行可视化展示。结果:纳入123篇文献,年度发文总量呈波动上升趋势,文献来源以苏州大学的硕博士论文为首,吴成翰团队及邹伟团队在该领域发文量较大;苏州大学是该领域发文量最高的机构;研究热点集中在自噬与凋亡在脑出血中的机制研究及中医干预研究;主题词的聚类分析比较显著;突现的关键词为脱证、闭证、自噬、凋亡、炎症、小胶质细胞,是脑出血自噬领域的研究热点。结论:脑出血的自噬研究领域前景良好,研究者相互合作,初具规模,机构间合作略欠佳,目前此领域的研究主要以药物干预的临床基础研究为主,这些成果为脑出血的自噬应用研究提供依据。Objective:To vanalyze0x09 the literatures of autophagy in intracerebral hemorrhage,and to explore the trend of research on autophagy after intracerebral hemorrhage.Methods:The articles about autophagy in intracerebral hemorrhage published on China National Knowledge Infrastructure(CNKI)from January 1,1991 to December 1,2022 were retrieved.CiteSpace and VOSviewer software were used to analyze and retrieve the author,subject,source distribution,quantity,etc.,and perform visual display.Results:One hundred twenty-three literatures were included,and the annual total number of articles was on the rise.The literature sources were mainly the master and doctoral theses of Soochow University.Wu Chenghan's team and Zou Wei's team had the largest number of research articles.Soochow University was the institution with the highest number of publications in this field.The research focuses on the mechanism of autophagy and apoptosis in cerebral hemorrhage and the intervention of traditional Chinese medicine.The key words were atelectasis,autophagy,apoptosis,inflammation,and microglia.It was a research hotspot in the field of autophagy in intracerebral hemorrhage.Conclusion:The research field of autophagy in intracerebral hemorrhage shows better prospect,researchers cooperate with each other,but there still lacks inter-agency co-operation.At present,the research in this field focuses on clinical research of drug intervention,which provides the basis for the application research of autophagy in intracerebral hemorrhage.

关 键 词：脑出血 自噬 CITESPACE VOSviewer 可视化分析 

分 类 号：R743.34[医药卫生—神经病学与精神病学] G353.1[医药卫生—临床医学]