Unravelling the genetic basis for skeletal muscle mitochondrial DNA copy number variations in pigs  

作　　者：Jiawen Yang Leilei Cui Yifeng Zhang Ziqi Ling Zhou Zhang Yizhong Huang Junwu Ma Shijun Xiao Bin Yang Lusheng Huang 

机构地区：[1]National Key Laboratory for Swine Genetic Improvement and Germplasm Innovation,Jiangxi Agricultural University,Nanchang 330045,China [2]School of Life Sciences,Nanchang University,Nanchang 330047,China

出　　处：《Science China(Life Sciences)》2024年第1期211-214,共4页中国科学（生命科学英文版）

基　　金：This work was supported by the National Key Research and Development Program of China(2021YFF1000601).

摘　　要：Dear Editor,Mitochondria are the center of cellular energy generation and free radical metabolism,with important functions in regulating intracellular calcium levels,cell apoptosis,cell cycle and epigenetic modifications.Mitochondrial DNA copy number(mtDNA-CN)is an indicator of mitochondrial biogenesis and has been associated with several diseases,such as cardiovascular disease,depression,chronic kidney disease and aging in humans(Clyde,2022).

关 键 词：METABOLISM CARDIOVASCULAR DISEASES 

分 类 号：S828[农业科学—畜牧学]