难治性抑郁症的精神外科治疗新进展  

New advances in minimally invasive or noninvasive surgery for refractory depression

作　　者：金柳荫 司璐佳 徐文倩 肖玲[1] 王高华[1] JIN Liu-yin;SI Lu-jia;XU Wen-qian;XIAO Ling;WANG Gao-hua(Department of Psychiatry,the People's Hospital of Wuhan University,Wuhan 430061,China)

机构地区：[1]武汉大学人民医院,430060

出　　处：《临床精神医学杂志》2024年第1期68-70,共3页Journal of Clinical Psychiatry

摘　　要：抑郁症是一种常见的精神障碍,在诊断为抑郁症的患者中大约有1/3的患者被诊断为难治性抑郁症,给患者的个人和家庭带来了严重的心理负担。近年来精神外科微创或无创手术方法的发展,使用外科手术方式治疗难治性抑郁症成为了可能。本文讨论了深部脑刺激,经颅直流电刺激,迷走神经刺激术,伽马刀,磁共振引导下的高强度聚焦超声内囊前肢损毁术等手术方法治疗难治性抑郁症的进展,以期给临床提供新的治疗思路。An estimated one third of depressed patients are diagnosed with treatment-resistant depression(TRD).TRD is characterized by failing to respond to two or more trials of antidepressant therapies,resulting in severe psychological burden to the patients’individuals and families.Recent advances in minimally invasive or noninvasive surgical methods have made it possible to treat TRD surgically.This paper discusses the progress of deep brain stimulation,transcranial direct current stimulation,vagal nerve stimulation,gamma knife,magnetic resonance guided high intensity focused ultrasound in treating TRD,in order to provide new ideas for clinical treatment.

关 键 词：难治性抑郁症 精神外科手术 

分 类 号：R749[医药卫生—神经病学与精神病学]