肠道菌群代谢产物在结肠炎相关结直肠癌中的作用  

Role of Intestinal Flora Metabolites in Colitis⁃associated Colorectal Cancer

作　　者：林小燕[1] 陈雪娥[2] 王承党[1] LIN Xiaoyan;CHEN Xuee;WANG Chengdang(Department of Gastroenterology,the First Affiliated Hospital of Fujian Medical University,Fujian Provincial Clinical Research Center of Liver and Intestinal Diseases,Fuzhou,350005;National Regional Medical Center,Binhai Campus of the First Affiliated Hospital of Fujian Medical University,Fuzhou)

机构地区：[1]福建医科大学附属第一医院消化内科福建省肝病和肠道疾病临床研究中心,350005 [2]福建医科大学附属第一医院滨海院区国家区域医疗中心

出　　处：《胃肠病学》2023年第5期297-301,共5页Chinese Journal of Gastroenterology

基　　金：福建省中青年教师教育科研项目(JAT200120)。

摘　　要：炎症性肠病(IBD)患者罹患结肠炎相关结直肠癌(CAC)的风险显著增加,肠道菌群代谢产物与CAC的关系备受关注,通过调节肠道菌群代谢或增加有益代谢产物可能对预防CAC具有重要作用。本文就肠道菌群代谢产物在CAC中的作用作一综述。Patients with inflammatory bowel disease(IBD)are at a significantly increased risk of colitis⁃associated colorectal cancer(CAC).The relationship between intestinal flora metabolites and CAC has attracted much attention.Regulating intestinal flora metabolism or increasing beneficial metabolites may play an important role in preventing CAC.This article reviewed the role of intestinal flora metabolites in CAC.

关 键 词：肠道菌群 代谢 炎症性肠病 结直肠肿瘤 

分 类 号：R735.34[医药卫生—肿瘤]