迷走神经参与肠易激综合征中肠-脑互动紊乱的研究进展  

Advances in Study on Role of Vagus Nerve in Gut⁃brain Interaction Disorder in Irritable Bowel Syndrome

作　　者：陈奇[1] 姜亚[1] 汤玉蓉[1] 姜柳琴[1] CHEN Qi;JIANG Ya;TANG Yurong;JIANG Liuqin(Department of Gastroenterology,the First Affiliated Hospital of Nanjing Medical University,Nanjing,210029)

机构地区：[1]南京医科大学第一附属医院消化内科,210029

出　　处：《胃肠病学》2023年第5期307-311,共5页Chinese Journal of Gastroenterology

摘　　要：迷走神经是肠-脑轴的重要组成部分,参与调节肠道运动和分泌,人体情绪反应和免疫应答,以及肠易激综合征(IBS)患者的肠-脑互动紊乱。本文就迷走神经及其功能,肠-脑轴中迷走神经功能异常与IBS发病的关系,以及迷走神经在IBS治疗中的应用等方面作一综述,以期提高对迷走神经功能与IBS中肠-脑互动紊乱关系的认识,了解其潜在治疗方法。The vagus nerve serves as an important part of the gut⁃brain axis,which regulates intestinal movement and secretion,emotional and immune response,and is involved in gut⁃brain interaction disorder in patients with irritable bowel syndrome(IBS).This article provides an overview of the vagus nerve function,the relationship between vagus nerve dysfunction in gut⁃brain axis and pathogenesis of IBS,and the application of vagus nerve in IBS treatment,with the aim for helping clinicians to better understand the correlation between vagus nerve and gut⁃brain interaction disorder,and shedding light on potential treatment in IBS.

关 键 词：迷走神经 肠-脑互动 肠易激综合征 治疗 

分 类 号：R574.4[医药卫生—消化系统]