Representation of conspecific vocalizations in amygdala of awake marmosets  

作　　者：Guoqiang Jia Siyi Bai Yingxu Lin Xiaohui Wang Lin Zhu Chenfei Lyu Guanglong Sun Kang An Anna Wang Roe Xinjian Li Lixia Gao 

机构地区：[1]Department of Neurology of the Second Affiliated Hospital and Interdisciplinary Institute of Neuroscience and Technology,Zhejiang University School of Medicine,Hangzhou 310029,China [2]MOE Frontier Science Center for Brain Science and Brain-Machine Integration,School of Brain Science and Brain Medicine,Zhejiang University,Hangzhou 310058,China [3]Key Laboratory of Biomedical Engineering of Ministry of Education,College of Biomedical Engineering and Instrument Science,Zhejiang University,Hangzhou 310027,China [4]College of Information,Mechanical and Electrical Engineering,Shanghai Normal University,Shanghai 201418,China [5]Key Laboratory of Medical Neurobiology of Zhejiang Province,Zhejiang University School of Medicine,Hangzhou 310020,China

出　　处：《National Science Review》2023年第11期3-14,共12页国家科学评论（英文版）

基　　金：supported by the Science and Technology Innovation 2030-‘Research on Brain Science and Brain-Inspired Intelligence’(2021ZD0204101 and 2022ZD0205000)(China);the National Natural Science Foundation of China(32170991,32071097 and 31871056);the Zhejiang Natural Science Foundation(China,LD22H090003);the Ministry of Education Frontier Science Center for Brain Science and Brain-Machine Integration(Zhejiang University,China);the Project funded by theChina Postdoctoral Science Foundation(2023M733097)。

摘　　要：Human speech and animal vocalizations are important for social communication and animal survival.Neurons in the auditory pathway are responsive to a range of sounds,from elementary sound features to complex acoustic sounds.For social communication,responses to distinct patterns of vocalization are usually highly specific to an individual conspecific call,in some species.This includes the specificity of sound patterns and embedded biological information.We conducted single-unit recordings in the amygdala of awake marmosets and presented calls used in marmoset communication,calls of other species and calls from specific marmoset individuals.We found that some neurons(47/262)in the amygdala distinguished‘Phee’calls from vocalizations of other animals and other types of marmoset vocalizations.Interestingly,a subset of Phee-responsive neurons(22/47)also exhibited selectivity to one out of the three Phees from two different‘caller’marmosets.Our findings suggest that,while it has traditionally been considered the key structure in the limbic system,the amygdala also represents a critical stage of socially relevant auditory perceptual processing.

关 键 词：VOCALIZATION non-human primate MARMOSET AMYGDALA 

分 类 号：R338[医药卫生—人体生理学] R-332[医药卫生—基础医学]