体检人群血尿酸水平与身体成分、运动素质及心肺功能的相关性  

Correlation between serum uric acid level and body composition,exercise capacity and cardiopulmonary function in medical examination population

作　　者：刘珊[1] 崔佳 赵威[1] 何宏海 葛杰[1] 郝小燕 齐天一 王鹏[1] Liu Shan;Cui Jia;Zhao Wei;He Honghai;Ge Jie;Hao Xiaoyan;Qi Tianyi;Wang Peng(Medical Examination Center,Peking University Third Hospital,Beijing 100191,China)

机构地区：[1]北京大学第三医院体检中心,北京100191

出　　处：《中华健康管理学杂志》2024年第1期24-28,共5页Chinese Journal of Health Management

基　　金：北京大学第三医院2022年度慢性病防治与健康教育科研项目(BJMB0012022028013);北京大学第三医院临床重点项目(BYSYZD2021008);北京市海淀区卫生健康发展科研培育计划(HP2023-03-501001)。

摘　　要：目的分析体检人群血尿酸水平与身体成分、运动素质及心肺功能的相关性。方法本研究为横断面研究,连续选取2023年6月1日至10月1日北京大学第三医院体检中心符合纳排标准的83例体检人群,按是否患有高尿酸血症(HUA)分为HUA组(53例)和非HUA组(30例)。使用人体成分测试仪获取体重指数、内脏脂肪面积等指标;使用握力、纵跳、背力、坐位体前屈等监测仪获取各项运动素质指标;最后进行台阶指数测试评估心肺功能水平。采用t检验、χ^(2)检验比较两组临床特征差异,分析体检人群血尿酸水平与身体成分、运动素质及心肺功能的相关性。结果HUA组骨骼肌含量、体脂肪含量、体重指数及内脏脂肪面积均显著高于非HUA组[(31.92±5.60)比(26.11±6.19)kg、(23.66±9.33)比(17.19±5.00)kg、(26.53±3.68)比(23.27±3.59)kg/m^(2)、91.20(74.25,123.90)比68.25(56.25,90.48)cm 2],HUA组握力[右,32.70(25.25,40.30)比42.35(35.95,48.10)kg;左,30.30(24.10,36.48)比40.55(33.06,45.10)cm]、纵跳[24.20(20.60,32.23)比29.90(25.20,35.50)kg]、背拉力[65.60(51.75,78.00)比91.00(67.25,111.50)kg]及台阶指数[(51.00±9.07)比(59.03±12.23)]均显著低于非HUA组(均P<0.05)。台阶指数与患HUA风险降低呈正相关(OR=0.875,95%CI:0.793~0.966)(P<0.05)。结论体检人群血尿酸水平与心肺功能存在相关性,心肺功能越好,患HUA风险越低;但与身体成分及运动素质的关系尚不明确。ObjectiveTo investigate the correlation between blood uric acid level and body composition,exercise capacity,and cardiopulmonary function in medical examination population.MethodsIn this cross-sectional study,83 individuals who underwent physical examinations at Peking University Third Hospital from June 1,2023,to October 1,2023,and met the inclusion criteria were included.According to whether they had hyperuricemia(HUA),the participants were divided into HUA group(53 cases)and non-HUA group(30 cases).Body composition parameters,such as body mass index and visceral fat area,were measured with a body composition analyzer.Exercise capacity indicators,including grip strength,vertical jump,back strength,and sit-and-reach test,were measured using specific monitoring devices.Cardiopulmonary function was assessed using the stair index test.The clinical characteristics of the two groups were compared with t-tests or chi-square tests,and the correlation between uric acid levels and body composition,exercise capacity,and cardiopulmonary function was analyzed.ResultsThe HUA group had significantly higher skeletal muscle mass,body fat mass,body mass index,and visceral fat area when compared with the non-HUA group[(31.92±5.60)vs(26.11±6.19)kg,(23.66±9.33)vs(17.19±5.00)kg,(26.53±3.68)vs(23.27±3.59)kg/m^(2),91.20(74.25,123.90)vs 68.25(56.25,90.48)cm^(2),respectively](all P<0.05).The grip strength,vertical jump,and back pull strength were all lower in the HUA group[32.70(25.25,40.30)vs 42.35(35.95,48.10)kg,30.30(24.10,36.48)vs 40.55(33.06,45.10)kg,24.20(20.60,32.23)vs 29.90(25.20,35.50)cm,65.60(51.75,78.00)vs 91.00(67.25,111.50)kg,respectivley](all P<0.05).The increased step index was positively correlated with reduced risk of hyperuricemia(OR=0.875,95%CI:0.793-0.966)(P<0.05).ConclusionsBlood uric acid level is correlated with cardiopulmonary function in medical examination population.Individuals with better cardiopulmonary function have a lower risk of developing HUA.However,the relationship between blood uric acid level

关 键 词：高尿酸血症 身体成分 运动素质 心肺功能 运动干预 

分 类 号：R194.3[医药卫生—卫生事业管理]