中西医结合治疗重症急性胰腺炎的难点与展望  

Difficulties and prospects of combined traditional Chinese and Western medicine in the treatment of severe acute pancreatitis

作　　者：夏庆[1] 邓力珲[1] 杜丹[1] 胡诚[1] 石娜[1] XIA Qing;DENG Lihui;DU Dan;HU Cheng;SHI Na(West China Center of Excellence for Pancreatitis,Institute of Integrated Traditional Chinese and Western Medicine,West China Hospital,Sichuan University,Chengdu 610041,P.R.China)

机构地区：[1]四川大学华西医院中西医结合中心,胰腺炎中心,成都610041

出　　处：《中国普外基础与临床杂志》2024年第2期129-133,共5页Chinese Journal of Bases and Clinics In General Surgery

基　　金：四川省中医药管理局重大项目(项目编号:2023ZD04)。

摘　　要：尽管重症急性胰腺炎(severe acute pancreatitis,SAP)的治疗已取得一些进展,仍然存在阻碍疗效再提高的因素:缺乏准确易行的早期严重程度预测体系,多学科协作机制有待进一步优化,尚无中医药临床疗效评价体系,中医药治疗靶点不清、效应物质不明、新药研发困难。为进一步降低SAP病死率、实现疗效再提高的目标,应加强中西医融合、多学科协作,进一步提高诊疗水平,以临床价值为导向开展基础与临床研究,“说明白”中医药的疗效,“讲清楚”其机制,将研究成果转化为SAP诊疗产品。针对SAP这一重大疑难疾病,应坚持守正创新、中西医协同、优势互补,推进中西医结合治疗SAP的创新发展,进一步降低病死率,减轻疾病负担。Despite of the progress in the treatment of severe acute pancreatitis(SAP),there are still factors that hinder the improvement of the efficacy of treatment:there is a lack of an accurate and easy-to-use system for early severity prediction;the multidisciplinary collaboration mechanism needs to be further optimized;there is no clinical efficacy evaluation system for traditional Chinese medicine(TCM);the therapeutic targets of TCM are unclear;the effector substances are unknown;and the research and development of new medicines is still difficult.In order to further reduce the mortality of SAP and realize the goal of improving the efficacy,we should strengthen the integration of Chinese and Western medicine,multidisciplinary collaboration,and improve the treatment levels;as well as carry out basic and clinical research oriented to clinical value.We will also promote the innovative development of combined Chinese and Western medicine in the treatment of SAP by elucidating the mechanism,validating the efficacy and commercializing the achievements.In view of SAP,a major and difficult disease,we should insist on the principle of integrity and innovation,the synergy of Chinese and Western medicines and the complementarity of advantages,and promote the innovation and development of combined Chinese and Western medicines in the treatment of SAP,so as to further reduce the morbidity and mortality and to alleviate the burden of the disease.

关 键 词：急性胰腺炎 中医药 多学科诊治 中西医结合治疗 

分 类 号：R576[医药卫生—消化系统]