微营养素在恶性肿瘤营养治疗中的应用现状  

Role and application of micronutrients in nutritional support for malignant tumors

作　　者：陈丽如[1] 丁丽丽[1] 叶文峰 朱明炜[3] Chen Liru;Ding Lili;Ye Wenfeng;Zhu Mingwei(Department of Clinical Nutrition,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing 100730,China;Department of Nutrition,Sun Yat-sen University Cancer Center,Guangzhou 510000,China;Department of General Surgery,Beijing Hospital,National Center of Gerontology,Institute of Geriatric Medicine,Chinese Academy of Medical Sciences,Beijing 100730,China)

机构地区：[1]北京医院临床营养科、国家老年医学中心、中国医学科学院老年医学研究院,100730 [2]中山大学附属肿瘤医院营养科,广州510000 [3]北京医院普通外科、国家老年医学中心、中国医学科学院老年医学研究院,100730

出　　处：《中华临床营养杂志》2023年第6期378-382,共5页Chinese Journal of Clinical Nutrition

基　　金：国家重点研发计划(2022YFC2010101);中央高水平医院临床科研业务费(BJ-2023-152);中国医学科学院医学与健康科技创新工程项目(2021-I2M-C&T-B-094);中华国际医学交流基金(Z-2017-24-2211)。

摘　　要：微营养素(micronutrients,MNs)包括维生素和微量元素,具有维持机体新陈代谢和免疫功能等不可或缺的作用。恶性肿瘤患者易合并多种MNs缺乏的营养不良,严重者影响器官功能和恶化临床结局。MNs从不同角度和途径与肿瘤的发生发展密切相关,及时通过肠外或肠内营养途径足量补充MNs,可使肿瘤患者临床受益。近年国内外多个指南发布了MNs在各种场景下的临床应用推荐意见,是指导肿瘤患者医学营养规范应用、改善预后的科学依据。Micronutrients(MNs),including vitamins and trace elements,play an indispensable role in human metabolism,immune function and other aspects.Due to the chronic microinflammation and long-term chemoradiotherapy,patients with malignant tumors often suffer from malnutrition,resulting in different degrees of MNs deficiency.In severe cases,MNs deficiency is closely related to the adverse clinical outcomes.Therefore,reasonable MNs supplementation is of great significance in improving the prognosis and quality of life of patients with tumors.Recently,multiple guidelines have made recommendations on the application of MN supplementation in various clinical settings,providing evidence for the standardized MN supplementation in patients with malignant tumors.

关 键 词：微营养素 维生素 微量元素 恶性肿瘤 营养治疗 

分 类 号：R730[医药卫生—肿瘤] R459.3[医药卫生—临床医学]