中医导引功法组方治疗血管性轻度认知障碍的疗效研究  

Study on the curative effect of traditional Chinese medicine Qigong prescription on vascular mild cognitive impairment

作　　者：王婧[1] 蔡春茜[2] 陈晓娜[1] 王雪[1] 薛米娜[1] 牛亚利[1] Wang Jing;Cai Chunqian;Chen Xiaona;Wang Xue;Xue Mina;Niu Yali(Department of Rehabilitation Medicine,General Hospital of Tianjin Medical University,Tianjin 300052,China;Department of Acupuncture,The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,Tianjin 300000,China)

机构地区：[1]天津医科大学总医院康复医学科,天津300052 [2]天津中医药大学第一附属医院针灸部,天津300000

出　　处：《国际医药卫生导报》2024年第4期651-656,共6页International Medicine and Health Guidance News

基　　金：国家自然科学基金青年项目(81802241)。

摘　　要：目的探讨中医导引功法组方治疗血管性轻度认知功能障碍(vascular mild cognitive impairment,VaMCI)的疗效。方法本研究为横断面研究。选取2017年1月至2019年1月在天津医科大学总医院康复医学科就诊的VaMCI患者50例作为研究对象,按随机数字表法将患者分为导引功法组25例[男12例、女13例,年龄(67.20±5.37)岁]和常规治疗组25例[男13例、女12例,年龄(67.36±5.38)岁]。另选取无疾病人群25例为正常组[男11例、女14例,年龄(67.04±4.36)岁]。常规治疗组给予基础治疗及常规运动功能康复训练,导引功法组在常规治疗组基础上经专业人员指导进行导引功法训练,疗程均为12周。对比3组治疗前后收缩压、舒张压及简易智力状态检查量表(MMSE)、蒙特利尔认知评估量表(MoCA)、洛文斯顿认知功能评定量表(LOTCA)及改良Barthel指数(MBI)评分。采用χ^(2)检验、t检验、方差分析。结果治疗12周后,导引功法组的MMSE评分、MoCA评分、MBI评分、注意力评分、视运动组织评分、思维操作评分及LOTCA总评分均高于常规治疗组[(23.64±2.90)分比(21.56±1.90)分、(23.72±2.42)分比(20.64±2.40)分、(75.80±7.31)分比(71.20±7.94)分、(3.12±0.73)分比(2.56±0.58)分、(21.96±1.90)分比(19.56±1.98)分、(26.16±1.89)分比(24.44±2.58)分、(96.20±4.25)比(90.44±6.58)分],导引功法组的收缩压、舒张压均低于常规治疗组[(137.00±10.70)mmHg(1 mmHg=0.133 kPa)比(147.60±8.91)mmHg、(73.80±10.23)mmHg比(85.40±10.60)mmHg],差异均有统计学意义(均P<0.05)。导引功法组治疗12周后的MMSE评分、收缩压、舒张压与正常组比较差异均无统计学意义[(23.64±2.90)分比(23.52±2.20)分、(137.00±10.70)mmHg比(138.80±7.94)mmHg、(73.80±10.23)mmHg比(73.40±10.08)mmHg](均P>0.05)。导引功法组治疗前后MMSE、MoCA、MBI、注意力、定向力、视运动组织、思维操作评分、LOTCA总分、收缩压的差值均大于常规治疗组和正常组(均P<0.05Objective To investigate the therapeutic effect of traditional Chinese medicine(TCM)Qigong prescription on vascular mild cognitive impairment(VaMCI).Methods This was a cross-sectional study.Fifty VaMCI patients treated in Department of Rehabilitation Medicine,General Hospital of Tianjin Medical University from January 2017 to January 2019 were selected as the study objects,and were divided into a Qigong therapy group[25 cases,12 males and 13 females,aged(67.20±5.37)years]and a conventional treatment group[25 cases,13 males and 12 females,aged(67.36±5.38)years]according to the random number table method.Another 25 persons without diseases were selected as a normal group[11 males and 14 females,aged(67.04±4.36)years].The conventional treatment group was given basic treatment and routine motor function rehabilitation training,and the Qigong therapy group was given Qigong prescription training on the basis of the conventional treatment group under the guidance of professionals.The overall course of treatment was 12 weeks.The systolic blood pressure(SBP),diastolic blood pressure(DBP),and scores of Mini-Mental State Examination(MMSE),Montreal Cognitive Assessment(MoCA),Loewenstein Occupational Therapy Cognitive Assessment(LOTCA),and modified Barthel index(MBI)were measured before and after treatment in the three groups.χ^(2)test,t test,and variance analysis were used.Results After 12 weeks of treatment,the MMSE score,MoCA score,MBI score,attention score,visual motor organization score,thinking operation score,and total LOTCA score of the Qigong therapy group were higher than those of the conventional treatment group[(23.64±2.90)points vs.(21.56±1.90)points,(23.72±2.42)points vs.(20.64±2.40)points,(75.80±7.31)points vs.(71.20±7.94)points,(3.12±0.73)points vs.(2.56±0.58)points,(21.96±1.90)points vs.(19.56±1.98)points,(26.16±1.89)points vs.(24.44±2.58)points,(96.20±4.25)points vs.(90.44±6.58)points];the SBP and DBP of the Qigong therapy group were lower than those of the conventional treatment group[(137

关 键 词：中医 导引 血管性轻度认知功能障碍 认知功能 日常生活活动能力 

分 类 号：R248.9[医药卫生—中医临床基础]