胰腺癌肝转移的治疗进展  

Progress in the treatment for pancreatic cancer with liver metastasis

作　　者：张传钊 陈汝福 Zhang Chuanzhao;Chen Rufu(Center of Pancreas,Guangdong Provincial People s Hospital(Guangdong Academy of Medical Sciences),Southern Medical University,Guangzhou 510080,China)

机构地区：[1]南方医科大学附属广东省人民医院(广东省医学科学院)胰腺中心,广州510080

出　　处：《中华转移性肿瘤杂志》2023年第4期440-443,共4页Chinese Journal of Metastatic Cancer

摘　　要：胰腺癌肝转移发生率高,是导致胰腺癌难治性的重要问题。近年来随着外科技术、基因检测、综合治疗等水平的提高,对胰腺癌肝转移的研究取得了一定的进展和成果。胰腺癌肝转移治疗前的个体化评估是制定个体化治疗方案的重要基础。对于胰腺癌肝脏寡转移者,选择合适的患者进行手术治疗可取得良好的预后。对于转移灶负荷较高者,应结合局部治疗和系统治疗,尽量延长患者生存时间。未来还需要更多的循证医学证据来指导胰腺癌肝转移的治疗。本文就国内外最新的研究结果并结合本中心的临床实践经验,对胰腺癌肝转移的诊治进展进行系统综述。The high incidence of liver metastasis in pancreatic cancer is the main reason for its refractoriness.In recent years,with the improvement of surgical techniques,gene testing,and comprehensive treatment,many progress has been made in liver metastasis of pancreatic cancer.Individualized assessment prior to treatment is an important basis for developing an individualized treatment program.A specific proportion of patients with oligo-metastatic pancreatic cancer could achieve a good prognosis with surgical treatment,while the patients with higher metastatic load should receive both local and comprehensive treatment to prolong the overall survival.More evidence-based medical evidence is needed to guide the management of liver metastasis of pancreatic cancer in the future.In this paper,we provide a systematic review of recent advances in treatment of liver metastasis of pancreatic cancer with the combination of the latest research findings at home and abroad and our clinical practice experience.

关 键 词：胰腺癌 肝转移 外科治疗 综合治疗 

分 类 号：R735.9[医药卫生—肿瘤]