中老年人群内脏脂肪代谢评分与新发脑卒中的相关性分析  

Analysis of the relationship between metabolism score for visceral fat andnew stroke in middle-aged and elderly population

作　　者：韩向东 李国徽 陈佳 HAN Xiang-dong;LI Guo-hui;CHEN Jia(Ningxia Medical University,Yinchuan,Ningxia 750001,China)

机构地区：[1]宁夏医科大学,宁夏银川750001 [2]银川市中医医院,宁夏银川750001

出　　处：《现代预防医学》2024年第3期417-421,共5页Modern Preventive Medicine

基　　金：银川市科技创新重大重点专项(2021-SF-003)。

摘　　要：目的 探讨中老年人内脏脂肪代谢评分(METS-VF)与新发脑卒中之间的关系。方法 使用2011和2018年中国健康与养老追踪调查(CHARLS)的数据建立三个logistic回归模型以研究METS-VF与新发脑卒中之间的关联,并采用限制立方样条模型检查可能的非线性关系。结果 纳入了7 007名研究对象,其中有407人出现新发脑卒中。回归模型结果显示,与METS-VF指数最低组Q1相比,METS-VF指数最高组Q4的新发脑卒中风险最高,患病风险增加了153%(OR=2.53,95%CI:1.87~3.47)。通过限制性三次样条回归分析发现,METS-VF指数与新发脑卒中患病率存在剂量反应关系(P<0.001),并且呈现J型关系(PNonliner<0.001)。结论 METS-VF指数与新发脑卒中患病率密切相关,并且两者存在剂量-反应关系。Objective To investigate the relationship between the metabolism score for visceral fat(METS-VF)and new stroke cases in the middle-aged and elderly.Methods Three Logistic regression models were established based on the data of China Health and Retirement Longitudinal Study(CHARLS)in 2011 and 2018 to study the association between METS-VF and new stroke cases,and the restricted cubic spline model was used to investigate the possible nonlinear relationship.Results In total 7007 participants were included,of which 407 had new stroke.The results of regression model showed that compared with the group with the lowest METS-VF index(Q1),the group with the highest METS-VF index(Q4)had the highest risk of new stroke,with the increased risk by 153%(OR=2.53,95%CI:1.87-3.47).Restricted cubic spline regression analysis found that there was a dose-response relationship between METS-VF index and the prevalence of new stroke(P<0.001),showing a J-shape relationship(P Nonlinear<0.001).Conclusion METS-VF index is closely related to the prevalence of new stroke,and there is a dose-response relationship between them.

关 键 词：中老年人 内脏脂肪代谢评分 新发脑卒中 剂量-反应关系 CHARLS 

分 类 号：R743.3[医药卫生—神经病学与精神病学] R589.2[医药卫生—临床医学]