小窝蛋白1与脑梗死相关性研究进展  

Research Progress in the Correlation between Caveolin-1 and Cerebral Infarction

作　　者：李晓岚 黄建敏[2] LI Xiaolan;HUANG Jianmin(Graduate School of Youjiang Medical University for Nationalities,Baise 533000,China;不详)

机构地区：[1]右江民族医学院研究生学院,广西百色533000 [2]右江民族医学院附属医院神经内科,广西百色533000

出　　处：《中国医学创新》2024年第5期175-179,共5页Medical Innovation of China

摘　　要：小窝蛋白1(caveolin-1,Cav-1)是小窝中的一种支架蛋白和胆固醇结合蛋白,是细胞膜穴样内陷的主要结构成分,在脂质转运、细胞生长分化、血管生成等方面有着重要的作用。Cav-1在中枢神经系统的内皮细胞、周细胞、星形胶质细胞等许多细胞中表达。现有研究表明Cav-1与多种中枢神经系统疾病之间存在密切联系,本文简要概述Cav-1与脑梗死的关系。Caveolin-1(Cav-1)is a scaffold protein and cholesterol binding protein in caveolae.It is the main structural component of cell membrane hole-like invagination,and plays an important role in lipid transport,cell growth and differentiation,angiogenesis and other aspects.Cav-1 is expressed in many other cells,including endothelial cells,pericytes,and astrocytes of the central nervous system.Existing studies indicate a close link between Cav-1 and multiple central nervous system diseases,which provide a brief overview of the relationship between Cav-1 and cerebral infarction.

关 键 词：小窝蛋白1 脑梗死 动脉粥样硬化 血管生成 

分 类 号：R743.33[医药卫生—神经病学与精神病学]