南通大学附属海门医院2020—2021年胃镜检查确诊上消化道恶性肿瘤流行病学分析  

Epidemiological study on upper gastrointestinal malignant tumor diagnosed by combination of gastroscopy and pathological analysis during 2020—2021 from Haimen Hospital Affiliated to Nantong University

作　　者：袁健 张健[2] YUAN Jian;ZHANG Jian(Department of Gastroenterology,Haimen Hospital Affiliated to Nantong University,Jiangsu Province,Haimen226100,China;Department of Pathology,Haimen Hospital Affiliated to Nantong University,Jiangsu Province,Haimen226100,China)

机构地区：[1]南通大学附属海门医院消化科,江苏海门226100 [2]南通大学附属海门医院病理科,江苏海门226100

出　　处：《中国当代医药》2024年第5期99-102,共4页China Modern Medicine

摘　　要：目的分析2020—2021年南通大学附属海门医院胃镜结合病理确诊上消化道恶性肿瘤患者的流行病学特点,为该地区上消化道恶性肿瘤的防治提供依据。方法收集南通大学附属海门医院消化内镜中心2020年1月至2021年12月所有电子胃镜检查病例,结合活检病理确诊恶性肿瘤的病例资料,分析其性别、年龄、胃镜诊断及病理结果等资料,排除既往已确诊上消化道恶性肿瘤及一人多次检查病例。采用Graphpad Prism 5进行数据分析。结果确诊上消化道恶性肿瘤1.64%(291/17712),男73.54%(214/291),女26.46%(77/291),年龄分布以65~<75岁比例最高,为40.89%(119/291),<55岁病例35例,均为胃癌。食管癌71例,胃癌202例,同时性胃癌合并食管癌3例,胃淋巴瘤11例,十二指肠球部癌3例,十二指肠降部癌1例;早期食管癌与胃癌37例,早癌诊断率为12.71%(37/291)。食管癌好发于食管中段59.16%(42/71),其次为食管下段胃结合部35.21%(25/71),食管上段癌发病率最低5.63%(4/71),病理分型以鳞癌为主90.14%(64/71)。胃癌病理分型均为腺癌,好发部位依次是胃窦45.05%(91/202)、胃体21.29%(43/202)、胃角19.8%(40/202)、贲门13.86%(28/202)。食管癌与胃癌平均检出年龄分别为(71.43±7.14)、(66.85±11.06)岁,胃癌的总体检出年龄低于食管癌,差异有统计学意义(t=2.566,P=0.013)。男女食管癌平均检出年龄分别为(71.05±7.37)、(74.21±7.89)岁,男性的食管癌检出年龄低于女性,差异有统计学意义(t=2.557,P=0.031);男女胃癌平均检出年龄分别为(66.43±10.58)、(66.84±12.53)岁,两组的检出年龄比较,差异无统计学意义(t=1.145,P=0.257)。结论南通大学附属海门医院确诊的上消化道恶性肿瘤主要为食管癌与胃癌,发病率男性高于女性,65~<75岁为上消化道恶性肿瘤高发年龄段,发病年龄胃癌低于食管癌,食管癌发病年龄男性低于女性,胃癌发病年龄男女无明显差异,胃癌发病年轻化及早癌检出率低需�Objective To investigate epidemiological characteristics of upper gastrointestinal malignant tumor diagnosed by combination of gastroscopy and pathological analysis in Haimen Hospital Affiliated to Nantong University during 2020—2021,to provide reference information for the prevention and treatment of upper gastrointestinal malignant tumor in the local area.Methods All electronic gastroscopy cases of Digestive Endoscopy Center of Haimen Hospital Affiliated to Nantong University from January 2020 to December 2021 were collected,and combined with the data of malignant tumors confirmed by biopsy and pathology,the data of gender,age,gastroscopy diagnosis and pathological results were analyzed,and the previously diagnosed upper digestive tract malignant tumors and multiple examination cases of one person were excluded.Data analysis was performed using Graphpad Prism 5.Results There were 1.64%(291/17712)of the patients were diagnosed with upper digestive tract malignant tumors,including 73.54%(214/291)in males and 26.46%(77/291)in females.The highest proportion of patients aged 65-<75 years was 40.89%(119/291),and 35 patients aged<55 years were gastric cancer.There were 71 cases of esophageal cancer,202 cases of gastric cancer,3 cases of concurrent gastric cancer combined with esophageal cancer,11 cases of gastric lymphoma,3 cases of duodenal bulbar cancer,and 1 case of descending duodenal cancer.There were 37 cases with early esophageal and gastric cancer,and the diagnosis rate was 12.71%(37/291).Esophageal cancer was most commonly found in the middle part of the esophagus(59.16%[42/71]),followed by the lower part of the esophagus(35.21%[25/71]),and the upper part of the esophagus had the lowest incidence(5.63%[4/71]),and the pathological type was mainly squamous cell carcinoma(90.14%[64/71]).The pathological types of gastric cancer were adenocarcinoma,and the most common sites were antrum 45.05%(91/202),body of stomach 21.29%(43/202),angle of stomach 19.8%(40/202)and cardia 13.86%(28/202).The mean detection age of

关 键 词：胃镜检查 胃癌 食管癌 早癌 检出率 

分 类 号：R735[医药卫生—肿瘤]