多系统萎缩诊断标准解读  

Interpretation of the 2022 diagnostic criteria for multiple system atrophy

作　　者：潘竞[1] 康佳 王新 海日罕 Pan Jing;Kang Jia;Wang Xin;Hai Rihan(Department of Internal Medicine,The Second Affiliated Hospital of Inner Mongolia Medical University,Hohhot 010020,China)

机构地区：[1]内蒙古医科大学第二附属医院内科中心,呼和浩特F010020

出　　处：《中华老年医学杂志》2024年第2期162-167,共6页Chinese Journal of Geriatrics

基　　金：内蒙古自然科学基金(2020MS08138);内蒙古自治区医疗卫生科技计划项目(202202216);内蒙古医科大学联合项目(YKD2022LH024)。

摘　　要：多系统萎缩(MSA)是一种严重的、进展迅速的神经系统退行性疾病,目前使用的诊断标准是2008年第二版MSA诊断标准,虽然在临床研究中得到广泛认可,但对疾病的早期诊断缺乏敏感性。MSA早期可靠的诊断对于患者护理和咨询、疾病修饰治疗临床试验的招募以及诊断工具的开发和验证尤为重要。为克服第二版诊断标准的不足,国际运动障碍协会开发了新的MSA诊断标准,并于2022年4月公开发表。本文对新版MSA诊断标准进行解读,并探寻今后研究工作中需要继续深入探索的科研领域,对于老年患者的管理和研究具有重要的指导意义。Multiple system atrophy(MSA)is a serious and rapidly progressive neurodegenerative disease.The currently used diagnostic criteria are the second edition of MSA diagnostic criteria published in 2008.Although widely recognized in clinical research,they lack sensitivity for early diagnosis of the disease.Reliable early diagnosis of MSA is particularly important for patient care and counseling,recruitment for clinical trials of disease-modifying therapies,and development and validation of diagnostic tools.To overcome the shortcomings of the second edition of the diagnostic criteria,the International Parkinson and Movement Disorder Society developed a new version of diagnostic criteria for MSA,which was published in April 2022.This paper interprets the new MSA diagnostic criteria and examines the scientific research areas that need to be further explored in future research,which will be important in guiding the management of elderly patients and related research.

关 键 词：多系统萎缩 前驱期 诊断共识 

分 类 号：R741[医药卫生—神经病学与精神病学]