彩色多普勒超声在健康体检人员甲状腺结节诊断中的应用价值  

The Value of Color Doppler Ultrasound in the Diagnosis of Thyroid Nodules in Health Check-up

作　　者：李芬芬 Li Fenfen(Yibicom Clinic,Guangzhou 510000,Guangdong Province,China)

机构地区：[1]视源综合门诊部,广东广州510000

出　　处：《中外医药研究》2023年第31期142-144,共3页JOURNAL OF CHINESE AND FOREIGN MEDICINE AND PHARMACY RESEARCH

摘　　要：目的:探究彩色多普勒超声在健康体检人员甲状腺结节诊断中的应用价值。方法:选取2022年1月—2023年8月于视源综合门诊部进行健康体检的受检者360例作为研究对象,均接受甲状腺彩色多普勒超声检查,并统计随访病理检查结果。将病理检查结果作为“金标准”,分析超声诊断结果以及良恶性甲状腺结节的超声影像特征。结果:360例受检者经过随访获得其病理诊断结果,证实恶性甲状腺结节54例、良性甲状腺结节306例。彩超诊断良性甲状腺结节296例、恶性甲状腺结节64例,其中误诊20例、漏诊10例。彩色多普勒超声诊断的特异度为93.46%、敏感度为81.48%、阳性预测值为68.75%、阴性预测值为96.62%。彩色多普勒超声诊断甲状腺结节性质的结果与病理检查结果的一致性较好(Kappa=0.801,P<0.001)。恶性甲状腺结节的形态不规整、边界不清晰、低回声、微钙化、薄厚不均、纵横比≥1、血流分布2级+3级的占比均高于良性甲状腺结节,差异有统计学意义(P<0.05)。结论:健康体检人员通过彩色多普勒超声诊断甲状腺结节的价值良好,敏感度、阴性预测值均较高,且彩色多普勒超声的影像特征有助于判定良恶性结节,值得临床推广。Objective:To investigate the application value of color Doppler ultrasound in the diagnosis of thyroid nodules in health check-up.Methods:360 examinees that underwent health checkups at Yibicom Clinic from January 2022 to August 2023 were selected as study subjects,all of whom received color Doppler ultrasound examination of the thyroid gland,and the results of the follow-up pathological examinations were counted.Results of pathological examination were used as the gold standard to ana⁃lyze the diagnostic results of ultrasound and ultrasonographic feature of benign and malignant thyroid nodules.Results:360 exam⁃inees obtained their pathologic diagnosis results in follow-up,confirming malignant thyroid nodules in 54 cases and benign thy⁃roid nodules in 306 cases.Color ultrasound diagnosed benign thyroid nodules in 296 cases and malignant thyroid nodules in 64 cases,of which 20 cases were misdiagnosed and 10 cases were missed.The specificity of color Doppler ultrasound diagnosis was 93.46%,its diagnostic sensitivity was 81.48%,positive predictive value was 68.75%,and negative predictive value was 96.62%.Results of color Doppler ultrasound of the nature of thyroid nodules were in good agreement with the results of pathological exami⁃nation(Kappa=0.801,P<0.001).The following indexes of malignant thyroid nodules were higher than those of benign thyroid nod⁃ules:irregular morphology,unclear borders,hypoechoicity,microcalcification,uneven thickness,anteroposterior transverse diam⁃eter ratio≥1,and blood flow distribution grade 2 and grade 3 and the difference was statistically significant(P<0.05).Conclusion:The application value of color Doppler ultrasound in diagnosis of thyroid nodules in health checkup is good,with high sensitivity and negative predictive value.Furthermore,color Doppler ultrasound helps to determine benign and malignant nodules.

关 键 词：健康体检 甲状腺结节 彩色多普勒超声 诊断 

分 类 号：R73[医药卫生—肿瘤]