急性脑卒中后循环大血管闭塞支架取栓与抽吸取栓的临床疗效及安全性  

Safety and clinical efficacy of stent and aspiration thrombectomy for posterior circulation large vessel occlusion in patients with acute stroke

作　　者：朱俊文 白福平 牟凌 ZHU Junwen;BAI Fuping;MOU Ling(Linfen Central Hospital,Linfen 041000,China)

机构地区：[1]临汾市中心医院,山西临汾041000

出　　处：《中国实用神经疾病杂志》2024年第4期431-435,共5页Chinese Journal of Practical Nervous Diseases

基　　金：山西省卫生健康委科研课题计划项目(编号:2020161)。

摘　　要：目的 探究后循环大血管闭塞急性脑卒中经支架取栓与抽吸取栓的临床疗效及安全性。方法 选取2021-03—2022-10临汾市中心医院收治的后循环大血管闭塞急性脑卒中患者48例为研究对象,研究组(25例)采用支架取栓予以治疗,对照组(23例)采用抽吸取栓治疗。比较2组基线资料、有效再灌注率、脑血管再通情况、并发症情况及改良Rankin量表(mRS)评分,评估两种治疗方案的有效性和安全性。结果 与治疗前相比,短期内2组有效灌注率、脑血管再通结局均明显上升(P<0.05),对照组血管再通时间明显长于研究组(P<0.05)。2组术后90 d内预后良好、病死率和不良反应发生率比较差异无统计学意义(P>0.05)。结论 支架取栓与抽吸取栓均可有效治疗急性缺血性脑卒中,两种治疗方案临床疗效及安全性相当。Objective To investigate the clinical efficacy and safety of stent thrombectomy and aspiration thrombectomy for posterior circulation large vessel occlusion in patients with acute stroke.Methods A total of 48 acute stroke patients with posterior circulation large vessel occlusion admitted to Linfen Central Hospital from March 2021 to October 2022 were selected as research objects.The study group(25 cases)was treated by stent removal,and the control group(23 cases)was treated by aspiration suppository therapy.The baseline data,effective reperfusion rate,cerebral vascular recanalization,complications,and modified Rankin scale(mRS)scores were compared between the two groups,and the efficacy and safety of the two treatment options were evaluated.Results Compared with before treatment,the short-term effective perfusion rate and cerebrovascular recanalization outcome of the two groups were significantly increased(P<0.05),but the recanalization time of the control group was significantly longer than that of the study group(P<0.05).There was no statistically significant difference in the comparison of good prognosis,morbidity and mortality rate and incidence of adverse reactions within 90 days after surgery between the two groups(P>0.05).Conclusion Both stent thrombectomy and aspiration thrombectomy can effectively treat acute ischemic stroke,and there is no difference in safety and clinical efficacy between the two treatments.

关 键 词：急性脑卒中 后循环大血管闭塞 支架取栓 抽吸取栓 安全性 

分 类 号：R743.3[医药卫生—神经病学与精神病学]