CT和MRI诊断儿童视网膜母细胞瘤的应用价值  

Application values of CT and MRI in diagnosis of retinoblastoma in children

作　　者：李壮[1] 杨凯华 吴玲 王重阳 周萌 马斌斌 LI Zhuang;YANG Kaihua;WU Ling;WANG Chongyang;ZHOU Meng;MA Binbin(Medical Imaging Department,Children’s Hospital Affiliated to Zhengzhou University,Zhengzhou Children’s Hospital of Henan Children’s Hospital,Zheng-zhou 450000,Henan,China)

机构地区：[1]郑州大学附属儿童医院/河南省儿童医院郑州儿童医院医学影像科,河南郑州450000

出　　处：《中国校医》2023年第11期848-850,共3页Chinese Journal of School Doctor

基　　金：2022年医学科技攻关项目(LHGJ20220761)。

摘　　要：目的 研究儿童视网膜母细胞瘤的计算机X线断层扫描(CT)、核磁共振(MRI)影像特征及诊断价值。方法 收集2021年8月—2022年5月郑州大学附属儿童医院收住的儿童视网膜母细胞瘤患儿52例,比较CT、MRI检查与病理检验的符合率,再观察所有患儿的CT、MRI影像特征,分析其诊断视网膜母细胞瘤的价值。结果 CT、MRI检查结果和病理学诊断结果的符合率为90.38%、94.23%,二者比较差异无统计学意义(χ^(2)=5.007,P=0.082)。CT检查患病病例图像上发现眼内高密度影,不均质,病灶中显示斑点、团块状钙化,CT值均>100 HU。MRI图像上发现T1WI低/中等信号,T2WI中/高等信号,T1WI、T2WI均存在片状低信号区。所有患儿经CT检查,图像上发现眼内高密度影,不均质,病灶中显示斑点、团块状钙化,CT值均>100 HU;经过增强扫描发现未钙化的病灶中出现不同程度的强化。所有患儿的眼环内存在软组织密度肿块,且边界清晰。41例患儿肿瘤生长位置处于眼环后位,同时伴有局部眼环增生的现象。结论 CT、MRI检查在儿童视网膜母细胞瘤的诊断中符合率较高,可考虑作为诊断此类患儿病情及预后的重要方法。Objective To study the imaging characteristics and diagnostic value of computed tomography(CT)and magnetic resonance imaging(MRI)of retinoblastoma in children.Methods A total of 52 children with retinoblastoma admitted to the Children’s Hospital of Zhengzhou University from August 2021 to May 2022 were enrolled and the coinci⁃dence rates of CT and MRI examinations with pathological examinations were compared.Then the CT and MRI characteris⁃tics of all children were observed to analyze their values in diagnosing retinoblastoma.Results The coincidence rates of CT and MRI results with pathological diagnosis results were 90.38%and 94.23%respectively,and there was no significant dif⁃ference between them(χ^(2)=5.007,P=0.082)。CT examination showed that the intraocular hyperdense shadow was heteroge⁃neous,and the lesions showed spots and clumpy calcifications with CT values>100 HU.MRI images showed that there were low/medium signals in T1WI,moderate/high signals in T2WI,and patchy hypo⁃intensity areas in T1WI and T2WI.After CT examination,all the children were found to have high⁃density and heterogeneous intraocular shadows on the images,and the lesions showed spots and clumpy calcifications with CT values>100 HU.After contrast⁃enhanced scanning,it was found that non⁃calcified lesions showed different degrees of enhancement.All children had a dense and well⁃defined soft tissue mass in the ocular rings.In the 41 cases of children,the tumor growth position was posterior to the ocular ring accompanied by local ocular ring hyperplasia.Conclusion CT and MRI examinations have a high coincidence rate in the diagnosis of retinoblas⁃toma in children and can be considered an important method for the diagnosis and prognosis of such children.

关 键 词：核磁共振 视网膜母细胞瘤 计算机X线断层扫描 儿童 

分 类 号：R739.7[医药卫生—肿瘤]