三步阶梯原则针灸法联合常规疗法治疗缓解期双相情感障碍失眠临床研究  

Clinical Study on Acupuncture and Moxibustion Method Based on Three Steps Principle Combined with Routine Therapy for Bipolar Disorder Complicated with Insomnia in Remission Stage

作　　者：王艳 钱秀莲 姜小琴 徐裕 徐鹏昊 余欣恬 WANG Yan;QIAN Xiulian;JIANG Xiaoqin;XU Yu;XU Penghao;YU Xintian(Quzhou Third Hospital,Quzhu Zhejiang 324000,China)

机构地区：[1]衢州市第三医院,浙江衢州324000

出　　处：《新中医》2024年第2期124-128,共5页New Chinese Medicine

摘　　要：目的:观察三步阶梯原则针灸法联合常规疗法治疗心脾两虚型缓解期双相情感障碍(BPD)失眠患者的临床效果。方法:回顾性分析200例心脾两虚型缓解期BPD失眠患者的临床资料,根据治疗方法的不同分为观察组与对照组各100例,2组均采取健康教育,服用碳酸锂缓释片与艾司唑仑片治疗,观察组加用三步阶梯原则针灸法治疗。2组均治疗2周。治疗前后评定匹兹堡睡眠质量指数(PSQI)评分、睡眠障碍评定量表(SDRS)评分、生活质量评估量表(SF-36)评分,统计实际睡眠总时间、睡眠效率、夜间觉醒时间。比较2组的临床疗效与治疗期间的不良事件发生率。结果:治疗后,观察组总有效率90.00%,对照组总有效率70.00%,2组比较,差异有统计学意义(P<0.05)。2组PSQI、SDRS评分均较治疗前下降(P<0.05);观察组PSQI、SDRS评分均低于对照组(P<0.05)。2组实际睡眠总时间均较治疗前延长,睡眠效率均较治疗前升高,夜间觉醒时间均较治疗前缩短,差异均有统计学意义(P<0.05)。观察组实际睡眠总时间长于对照组,睡眠效率高于对照组,夜间觉醒时间较对照组缩短,差异均有统计学意义(P<0.05)。2组SF-36评分均较治疗前升高(P<0.05);观察组SF-36评分高于对照组(P<0.05)。2组不良事件发生率比较,差异无统计学意义(P>0.05)。结论:在常规疗法基础上加用三步阶梯原则针灸法治疗心脾两虚型缓解期BPD失眠患者临床效果显著,可有效改善患者的失眠症状,提高睡眠质量和生活质量。Objective:To observe the clinical effect of acupuncture and moxibustion methods based on three steps principle combined with routine therapy on patients with bipolar disorder(BPD) complicated with insomnia in remission stage.Methods:The clinical data of 200 patients with BPD complicated with insomnia in remission stage of dual deficiency of the heart and spleen type were retrospectively analyzed and divided into the observation group and control group according to different treatment methods,with100 cases in each group.The two groups were treated with health education,Lithium Carbonate Sustained-Release Tablets and Estazolam Tablets,and the observation group was additionally given the acupuncture and moxibustion methods based on three steps principle for treatment.The two groups were treated for two weeks.Before and after treatment,the scores of Pittsburgh Sleep Quality Index(PSQI),Sleep Dysfunction Rating Scale(SDRS) and 36-item Short-Form(SF-36) were evaluated;the actual total sleep time,sleep efficiency and awakening time at night were counted;the clinical effects and incidence of adverse reactions were compared between the two groups.Results:After treatment,the total effective rate was 90.00% in the observation group and 70.00% in the control group,the difference being significant(P<0.05).The scores of PSQI and SDRS in both groups were decreased when compared with those before treatment(P<0.05),and the above scores in the observation group were lower than those in the control group(P<0.05).The actual total sleep time and sleep efficiency in both groups were increased when compared with those before treatment(P<0.05),and the sleep efficiency in both groups were decreased when compared with those before treatment(P<0.05).The actual total sleep time in the observation group was longer than that in the control group,the sleep efficiency was higher than that in the control group,and the awakening time at night was shortened when compared with that in the control group(P<0.05).The SF-36 scores in both groups were i

关 键 词：双相情感障碍 缓解期 失眠 心脾两虚证 针灸疗法 睡眠质量 生活质量 

分 类 号：R749[医药卫生—神经病学与精神病学]