Metallothionein 1E Alleviates Cadmium-induced Renal Cytotoxicity through Promoting Mitochondrial Functional Recovery  

作　　者：WEN Si Hui LI Lu Bei HUANG Hui Dan XIE Ying LUO Lei 

机构地区：[1]Key Laboratory of Molecular Epidemiology of Hunan Province,School of Medicine,Hunan Normal University,Changsha 410081,Hunan,China [2]Department of Occupational Health,Changsha Centre for Disease Control and Prevention,Changsha 410004,Hunan,China [3]The Key Laboratory of Model Animals and Stem Cell Biology in Hunan Province,Hunan Normal University School of Medicine,Changsha 410013,Hunan,China

出　　处：《Biomedical and Environmental Sciences》2024年第1期117-121,共5页生物医学与环境科学（英文版）

基　　金：supported by the National Natural Science Foundation of China[grant numbers 82103887];Hunan Provincial Natural Science Foundation of China[grant numbers 2021JJ30752 and 2021JJ40374];National Science Fund for Excellent Young Scholars of Hunan Province[grant numbers 2023JJ20032];Changsha Natural Science[grant numbers 45045]。

摘　　要：The pervasive utilization of industrial substances has escalated human exposure to cadmium(Cd),a metal associated with long-term negative health outcomes such as renal dysfunction,neurological disorders,and various cancers^([1]).Once ingested by humans,Cd interacts with cysteine-rich metallothioneins(MTs)which have metal-binding and antioxidant properties and is subsequently transported to the kidney^([2]).

关 键 词：RENAL KIDNEY CADMIUM 

分 类 号：R114[医药卫生—卫生毒理学]