1990—2019年中国龋病的疾病负担现状及变化趋势研究  

Current Situation and Trends in the Disease Burden of Dental Caries in China,1990-2019

作　　者：黄港 曹桂莹 刘民[2,3] HUANG Gang;CAO Guiying;LIU Min(Department of Stomatology,Beijing Shijitan Hospital,Capital Medical University,Beijing 100038,China;Department of Epidemiology and Biostatistics,School of Public Health,Peking University,Beijing 100191,China;Key Laboratory of Epidemiology of Major Diseases(Peking University),Ministry of Education,Beijing 100191,China)

机构地区：[1]首都医科大学附属北京世纪坛医院口腔科,北京市100038 [2]北京大学公共卫生学院流行病与卫生统计学系,北京市100191 [3]重大疾病流行病学教育部重点实验室(北京大学),北京市100191

出　　处：《中国全科医学》2024年第14期1735-1741,共7页Chinese General Practice

基　　金：科技创新2030重大项目(2021ZD0114104,2021ZD0114105,2021ZD0114101)。

摘　　要：背景龋病是常见的非传染性疾病之一,影响着全球三分之一以上的人口,分析其疾病负担现状及变化趋势能够为龋病的防治策略提供一定的参考价值。目的分析中国龋病的发病、患病和伤残损失寿命年(YLD)现状及变化趋势,为我国制订龋病防治策略提供参考依据。方法提取2019年全球疾病负担(GBD)研究中1990—2019年中国乳牙龋病和恒牙龋病的发病、患病和YLD数据,计算1990—2019年中国乳牙龋病和恒牙龋病的发病人次、患病人数和YLD人年数的变化百分比,并应用Joinpoint回归模型分析1990—2019年中国乳牙龋病和恒牙龋病的年龄标准化发病率、患病率和YLD率的年度变化百分比(APC)与平均年度变化百分比(AAPC)。结果与1990年相比,2019年中国乳牙龋病的发病人次、患病人数和YLD人年数分别减少了25.69%、28.74%和28.63%;恒牙龋病的发病人次、患病人数和YLD人年数分别增加了17.41%、15.84%和15.07%。2019年,在各年龄组中,5~9岁儿童乳牙龋病发病率(118.96%)最高,1~4岁儿童乳牙龋病患病率(53.08%)和YLD率(20.40/10万)最高;20~24岁成年人恒牙龋病的发病率(62.30%)、患病率(32.19%)和YLD率(32.41/10万)均最高。Joinpoint回归模型结果显示:1990—2019年,中国乳牙龋病的年龄标准化发病率(AAPC=0.21%,95%CI=0.19%~0.22%)、患病率(AAPC=0.03%,95%CI=0.01%~0.05%)和YLD率(AAPC=0.03%,95%CI=0.01%~0.05%)整体呈上升趋势;恒牙龋病的年龄标准化发病率(AAPC=-0.05%,95%CI=-0.05%~-0.04%)、患病率(AAPC=-0.23%,95%CI=-0.32%~-0.14%)和YLD率(AAPC=-0.22%,95%CI=-0.31%~-0.13%)整体呈下降趋势。结论中国1990—2019年乳牙龋病疾病负担呈现出加重趋势,尽管恒牙龋病的疾病负担有所下降但依旧严峻,预防龋病不能仅局限于儿童,而应该包括所有年龄段人群。Background Dental caries is one of the most common noncommunicable diseases worldwide,affecting more than one-third of the global population.The analysis of the current situation and trends in the disease burden of dental caries may provide a reference for the prevention and control strategies of dental caries.Objective To analyze the current situation and trends in the incidence,prevalence and years lived with disability(YLD)of dental caries in China and provide a reference for the development of the prevention and control of dental caries.Methods Data on the incidence,prevalence and YLD of caries of deciduous teeth and permanent teeth between 1990 and 2019 in China were extracted from the 2019 Global Burden of Disease(GBD)study.The percentage change in the counts of incident cases,prevalent cases and YLD of caries of deciduous teeth and permanent teeth from 1990 to 2019 was calculated,and Joinpoint regression model was used to analyze the annual percentage change(APC)and average APC(AAPC)in age-standardized rates of incidence,prevalence and YLD between 1990 and 2019 in China.Results Compared with 1990,the counts of incident cases,prevalent cases and YLD of caries of deciduous teeth in China in 2019 decreased by 25.69%,28.74%and 28.63%,respectively;the counts of incident cases,prevalent cases and YLD of caries of permanent teeth in China in 2019 increased by 17.41%,15.84%and 15.07%,respectively.In all age groups in 2019,the highest incidence rate(118.96%)of caries of deciduous teeth was observed in children aged 5 to 9 years,as well as the highest prevalence rate(53.08%)and YLD rate(20.40/100,000)of caries of deciduous teeth in children aged 1 to 4 years.The highest incidence rate(62.30%),prevalence rate(32.19%),and YLD rate(32.41/100000)of caries of permanent teeth were observed in adults aged 20 to 24 years in 2019.Joinpoint regression analysis showed that the agestandardized rates of incidence(AAPC=0.21%,95%CI=0.19%to 0.22%),prevalence(AAPC=0.03%,95%CI=0.01%to 0.05%)and YLD(AAPC=0.03%,95%CI=0.01%to 0.05%)of c

关 键 词：乳牙龋病 恒牙龋病 牙科生理学现象 Joinpoint回归模型 2019全球疾病负担研究 

分 类 号：R781.1[医药卫生—口腔医学]