Ten-year observation of corneal densitometry and associated factors following small incision lenticule extraction  

作　　者：Xiao-Song Han Fei Xia Zhuo-Yi Chen Pei-Jun Yao Dong-Mei Yang Jing Zhao Xing-Tao Zhou 

机构地区：[1]Eye Institute and Department of Ophthalmology,Eye&ENT Hospital,Fudan University,Shanghai 200031,China [2]NHC Key Laboratory of Myopia(Fudan University),Key Laboratory of Myopia,Chinese Academy of Medical Sciences,Shanghai 200031,China [3]Shanghai Research Center of Ophthalmology and Optometry,Shanghai 200031,China [4]Shanghai Engineering Research Center of Laser and Autostereoscopic 3D for Vision Care(20DZ2255000),Shanghai 200031,China

出　　处：《International Journal of Ophthalmology(English edition)》2024年第3期485-490,共6页国际眼科杂志（英文版）

摘　　要：●AIM:To investigate the long-term changes of corneal densitometry(CD)and its contributing elements after small incision lenticule extraction(SMILE).●METHODS:Totally 31 eyes of 31 patients with mean spherical equivalent of-6.46±1.50 D and mean age 28.23±7.38y were enrolled.Full-scale examinations were conducted on all patients preoperatively and during followup.Visual acuity,manifest refraction,axial length,corneal thickness,corneal higher-order aberrations,and CD were evaluated.●RESULTS:All surgeries were completed successfully without complications or adverse events.Ten-year safety index was 1.17±0.20 and efficacy 1.04±0.28.CD value of 0–6 mm zones in central layer was statistically significantly lower 10y postoperatively,compared with preoperative values(0–2 mmΔ=-1.62,2–6 mmΔ=-1.24,P<0.01).There were no correlations between CD values and factors evaluated.●CONCLUSION:SMILE is a safe and efficient procedure for myopia on a long-term basis.CD values get lower 10y postoperatively,whose mechanism is to be further discussed.

关 键 词：MYOPIA small incision lenticule extraction corneal densitometry 

分 类 号：R779.6[医药卫生—眼科]