Treatment of uveitis and scleritis patients in Malaysia  

作　　者：Sieng Teng Seow Iqbal Tajunisah Fei Yee Lee Pooi Wah Lott Sagili Chandrasekhara Reddy 

机构地区：[1]Department of Ophthalmology,University Malaya Eye Research Centre(UMERC),Faculty of Medicine,Universiti Malaya,Kuala Lumpur 59100,Malaysia [2]Clinical Research Centre,Selayang Hospital,Ministry of Health Malaysia,Selangor 68100,Malaysia [3]Department of Ophthalmology,Faculty of Medicine and Defence Health,National Defence University of Malaysia,Kuala Lumpur 57000,Malaysia

出　　处：《International Journal of Ophthalmology(English edition)》2024年第3期518-527,共10页国际眼科杂志（英文版）

摘　　要：●AIM:To determine the common causes and visual outcome after treatment among uveitis and scleritis patients.●METHODS:This is a retrospective cohort observational study.All consecutive clinical records of patients with newly diagnosed uveitis and scleritis over a 4-year period,from Jan.1,2017 to Dec.31,2020,were analysed.Data was collected at the presentation and included a follow-up period of one year.●RESULTS:A total of 288 patients were recruited during the study period.Anterior uveitis was the most common anatomical diagnosis(50.0%)followed by panuveitis(25.0%),scleritis(13.5%),posterior uveitis(6.9%),and intermediate uveitis(4.5%).Viral Herpes was the most common cause of infectious cases,while Vogt-Koyanagi-Harada(VKH)disease and human leucocyte antigen(HLA)B27 spondyloarthropathy were the leading causes of identifiable non-infectious cases.Majority of patients presented with unilateral,non-granulomatous uveitis with an absence of hypopyon.Anatomical locations like posterior uveitis and panuveitis,and visual acuity worse than 3/60 at presentation were the factors associated with poor visual outcomes(P<0.05).About 60%of patients had an identifiable cause for the uveitis and scleritis,with nearly equal distribution of infectious(n=85,29.5%)and noninfectious causes(n=84,29.2%).About 14.5%of patients were clinically blind at 1y of follow-up.The most common complication in our uveitis patients was glaucoma(47.5%),followed by cystoid macula oedema(18.9%)and cataract(13.9%).●CONCLUSION:Uveitis and scleritis are important causes of ocular morbidity.They are potentially blinding diseases which can have a good outcome if diagnosed and treated early.

关 键 词：UVEITIS SCLERITIS ocular morbidity BLINDNESS AETIOLOGY 

分 类 号：R772.3[医药卫生—眼科]