Stromal lenticule addition keratoplasty with corneal crosslinking for corneal ectasia secondary to FS-LASIK:a case series  

作　　者：Li-Xiang Wang Ying-Ping Deng Meng-Zhen Xie Ke Ma Hong-Bo Yin Qiong Wang Rui Gong Jing Tang 

机构地区：[1]Department of Ophthalmology,West China Hospital,Sichuan University,Chengdu 610041,Sichuan Province,China [2]West China School of Medicine,Sichuan University,Chengdu 610041,Sichuan Province,China

出　　处：《International Journal of Ophthalmology(English edition)》2024年第3期596-602,共7页国际眼科杂志（英文版）

基　　金：Supported by the Science&Technology Department of Sichuan Province(China)Funding Project(No.2021YFS0221,No.2023YFS0179);1.3.5 Project for Disciplines of Excellence,West China Hospital,Sichuan University(No.2022HXFH032,No.ZYJC21058);the Postdoctoral Research Funding of West China Hospital,Sichuan University,China(No.2020HXBH044).

摘　　要：●AIM:To explore the clinical efficacy and safety of stromal lenticule addition keratoplasty(SLAK)with corneal crosslinking(CXL)on patients with corneal ectasia secondary to femtosecond laser-assisted in situ keratomileusis(FS-LASIK).●METHODS:A series of 5 patients undertaking SLAK with CXL for the treatment of corneal ectasia secondary to FS-LASIK were followed for 4-9mo.The lenticules were collected from patients undertaking small incision lenticule extraction(SMILE)for the correction of myopia.Adding a stromal lenticule was aimed at improving the corneal thickness for the safe application of crosslinking and compensating for the thin cornea to improve its mechanical strength.●RESULTS:All surgeries were conducted successfully with no significant complications.Their best corrected visual acuity(BCVA)ranged from 0.05 to 0.8-2 before surgery.The pre-operational total corneal thickness ranged from 345-404μm and maximum keratometry(Kmax)ranged from 50.8 to 86.3.After the combination surgery,both the corneal keratometry(range 55.9 to 92.8)and total corneal thickness(range 413-482μm)significantly increased.Four out of 5 patients had improvement of corneal biomechanical parameters(reflected by stiffness parameter A1 in Corvis ST).However,3 patients showed decreased BCVA after surgery due to the development of irregular astigmatism and transient haze.Despite the onset of corneal edema right after SLAK,the corneal topography and thickness generally stabilized after 3mo.●CONCLUSION:SLAK with CXL is a potentially beneficial and safe therapy for advanced corneal ectasia.Future work needs to address the poor predictability of corneal refractometry and compare the outcomes of different surgical modes.

关 键 词：corneal ectasia femtosecond laserassisted in situ keratomileusis stromal lenticule addition keratoplasty corneal crosslinking corneal thickness corneal biomechanics 

分 类 号：R779.65[医药卫生—眼科]